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USA Today Bestseller The arrival of Buffalo Bill's Wild West show in London brings trouble. When the sharpshooter who beats Willie at poker is murdered, Matt and India investigate. Willie is convinced the victim cheated, but no one knows how until India discovers his secret - he was a paper magician. When their list of suspects grows to include a member of the mysterious magic Collector's Club, they uncover a spy. But who is he working for? And what does his employer want? As danger circles, secrets are revealed, and India struggles to keep her own secret hidden from Matt. But when her grandfather introduces her to a man who can change her life, India must decide if she wants her life to change at all.
For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy. The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.
When Charlie returns to Lichfield, she steps into chaos. The killer is still on the loose, Lady Harcourt's secret is out, Seth and Gus are gone, and Lady Vickers has come to stay. But nothing compares to the chaos inflicted on Charlie's heart by seeing Lincoln every day. Despite their frequent clashes, Lincoln and Charlie manage to work together to narrow their list of suspects. No one can be trusted, especially not the members of the committee who are not what they seem. Long buried pasts are dug up as Charlie and Lincoln attempt to restore peace to Lichfield. But when danger enters her home, Charlie's world is shattered.
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Gossip, scandal and murder collide on the express train to London. Did the journalist fall from the first-class carriage, or was she pushed? Cleo’s holiday with her family to the seaside resort town of Brighton is everything she hoped it would be…until she receives a blackmail note. The blackmailer demands Cleo help her or a story revealing Cleo’s investigating will appear in the newspaper. With her uncle warning her to keep her detecting activities private, Cleo agrees to meet the blackmailer when they return to London. But when the woman is seen getting on the train but not off, Cleo grows concerned. She enlists the help of the hotel staff to search for the body along the railway line. Finding it confirms her suspicions and leads her to discover that her blackmailer was a gossip columnist. What scandal had the victim uncovered that led to her death? And which fellow passenger had a secret worth killing for? With Harry Armitage’s assistance, Cleo attempts to track down the murderer. Meanwhile, pressure is mounting on the hotel staff to host a society wedding that will be featured in the social pages for all the right reasons.
The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. While considerable advances have been reported, there is still a signi- cant amount of work left to accomplish before our ambitions can be achieved. It now seems timely to review the accomplishments achieved to date and to clarify the challenges that remain. The choice of radionuclide, the conjugation p- cedure employed, and the selection of suitable targets were early issues that were faced by our field that still persist, however we can now tackle these obstacles with significantly better insight. The expanding array...
Reflecting the past 20 years of intense research in radioimmunotherapy, this timely reference surveys an expansive breadth of topics on the evolving developments in radiation therapy. Placed in the context of advances in cancer treatment, chapters progress systematically from basic principles and properties of radionuclides to detailed summaries of
This book covers foundational topics in the emerging field of radiopharmaceutical therapy. It is divided into three sections: fundamentals, deeper dives, and special topics. In the first section, the authors examine the field from a bird’s-eye view, covering topics including the history of radiopharmaceutical therapy, the radiobiology of radiopharmaceutical therapy, and the radiopharmaceutical chemistry of both metallic and non-metallic radionuclides. The second section provides a more in-depth look at specific radiotherapeutics. Chapters include broader discussions of the different platforms for radiopharmaceutical therapy as well as more focused case studies covering individual radiotherapeutics. The third and final section explores a number of areas for further study, including medical physics, artificial intelligence, in vivo pretargeting, theranostic imaging, and the regulatory review process for radiotherapeutics. This book is the first of its kind andis useful for a broad audience of scientists, researchers, physicians, and students across a range of fields, including biochemistry, cancer biology, nuclear medicine, radiology, and radiation oncology.
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