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Cancer Treatment Modalities: An Interdisciplinary Approach
The “Cancer Treatment Modalities: An Interdisciplinary Approach” is the twenty fourth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on cancer treatment. The volume starts with a chapter on an interdisciplinary approach to biomarker discovery for cancer treatment, followed by other chapters on multidisciplinary approach in cancer management; and the interplay between inflammation and cancer progression. Cancer stem cells and mesenchymal stem cells are discussed in cancer therapy in other chapters. RNA epigenetics in cancer diagnosis and treatment as well as different aspects of telomerase inhibitors in cancer treatment are the subjected of su...
Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.B)
Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.
Global research agenda for antimicrobial resistance in human health
Antimicrobial resistance is a significant global health threat, linked to 4.95 million deaths in 2019, with low- and middle-income countries experiencing disproportionately higher mortality rates. A global research agenda has been developed to prioritize impactful topics for mitigating antimicrobial resistance in human health, focusing on WHO priority bacterial and fungal pathogens, as well as drug-resistant Mycobacterium tuberculosis. Through a systematic review and expert consultation, 2340 knowledge gaps were distilled into 175 research topics, with the top 40 selected based on expert opinion of feasibility, policy relevance, impact, and equity. This agenda aims to direct investment and action to the most pressing and relevant research, ultimately translating priorities into fundable proposals, especially for resource-limited settings.
Coronavirus Disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management and Public Health Response, Volume II (volume I.A)
Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.
The Cyprus Gazette
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The Effect of Statins on the Incidence and Prognosis of Bladder Cancer: a Systematic Review and Meta-analysis
Abstract: Background: Statins are widely used due to their ability to lower plasma cholesterol and offer protection from the effects of atherosclerosis. However, their role in urology and specifically bladder cancer remains unclear. We aimed to systematically address this issue in the literature and determine any possible effects of statin therapy on bladder cancer. Methods: We searched MEDLINE (PubMed) and Cochrane Library databases for records up to 26 March 2023, for studies evaluating the effects of statins on urinary bladder cancer (UBC). We included all randomized controlled trials (RCTs), cohorts, and case-control studies that were conducted on the adult population. PROSPERO registrat...
