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This volume details molecular mechanisms that are involved in neuronal morphogenesis, and methods for analyzing these mechanisms. Chapters detail analyzing neuronal morphology in vitro and in vivo using a variety of model systems, including rodents and human induced pluripotent stem cells (hiPSCs). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Neuronal Morphogenesis: Methods and Protocols aims to be suitable for a wide range of readers interested in the mechanisms of neuronal morphology and related neurological disorders.
Johann Mathias Hütwohl (1711-1776) was born in Steeg, Germany, the son of John Georg Hütwohl. In 1744 he married Anna Christina and in 1748 they, along with two daughters, sailed for America. Anna Christina and the daughters died at sea. Johann arrived in Philadelphia and settled in the Conestoga valley. In 1765 he married a Miss Haas, and they became the parents of six children. Descendants and relatives lived in Pennsylvania, Virginia, Florida, and elsewhere in the United States, and throughout Canada.
Providing condensed descriptions of more than 500 methods compiled from Current Protocols in Cell Biology, this text thoroughly explores cell biology in an easily accessible, hands-on format. Short Protocols in Cell Biology is an authoritative and indispensable guide for all life scientists and researchers who are looking to improve their understanding of cell biology methods. Key Features: Designed to provide quick access to step-by-step instructions for the essential methods used in every major area of cell biological research Contains methods from every aspect of cell biology?everything needed to study the basic structure and functions of cells at both the molecular and cellular levels
No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-
Understanding the underlying mechanisms of how axons and dendrites develop is a fundamental problem in neuroscience and a main goal of research on nervous system development and regeneration. Previous studies have provided a tremendous amount of information on signaling and cytoskeletal proteins regulating axonal and dendritic growth and guidance. However, relatively little is known about the relative contribution and role of cytoskeletal dynamics, transport of organelles and cytoskeletal components, and force generation to axonal elongation. Advancing the knowledge of these biomechanical processes is critical to better understand the development of the nervous system, the pathological progr...