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Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological, and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target. - Provides an overview of neuroglia biology - Identifies normal neuroglia function in the healthy nervous system - Includes animal and human research - Discusses transcriptomic, electrophysiological, and imaging techniques to study neuroglia - Covers research using neuroglia as a therapeutic target
There is an assumption that environmental threats could cause important damages in central nervous system. As a consequence, several forms of brain structural plasticity could be affected. The environmentally mediated risks include generally physical (such as brain and spinal cord injury) and psychological / psychosocial influences (e.g. stress). In general, the response of the organism to these environmental challenges passes via adaptive responses to maintain homeostasis or functional recovery. These processes engage the immune system, the autonomic nervous system (ANS) besides the hypothalamo-hypophyseo-adrenal (HPA) axis via specific hormones, neurotransmitters, neuropeptides and other f...
Brain hypoxia-ischemia is a disorder characterised by a reduction in oxygen supply (hypoxia) combined with reduced blood flow (ischemia) to the brain. This condition may result from a localised obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ischemic attack, transient; brain infarction; brain oedema; coma; and other conditions. This book presents the latest research in this field from around the world.
The field of cerebrovascular diseases and cerebrospinal fluid disorders is a complex and evolving area of neurological research. These disorders present significant diagnostic and therapeutic challenges due to their diverse nature and intricate pathophysiological mechanisms. Recent advancements in molecular genetics and neuroimaging have significantly improved our understanding of these conditions, allowing for more precise identification of their underlying causes. Despite these advancements, there remain substantial gaps in our knowledge, particularly concerning the genetic features that contribute to these disorders. Ongoing exploration focuses on the integration of genetic insights into ...
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