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Pulmonary arterial hypertension (PAH) continues to be a condition associated with a high morbidity and mortality despite the advances in treatment strategies over the past 25 years. Although defined by strict hemodynamic criteria, PAH is a syndrome based on diverse etiologies and pathogenesis. PAH is characterized by excessive pulmonary vascular remodeling, pulmonary arterial obstruction and elevated pulmonary vascular resistance (PVR), which result in a marked increase in right ventricle (RV) afterload. Eventually, the RV is not able to cope with the increased load and HF develops.
Agasat de o doamnă care gira rubrica mondenă a unui ziar newyorkez, cu privire la preferinţele sale, la întrebarea care este obiectul său favorit din natură, Mark Twain a răspuns, în maniera sa unică: „O frumoasă mută!” Ziarist, traducător, autor de carţi, Irina Airinei îndeplineşte doar una dintre condiţii. Fiind universitar – doctor în filologie -, predând cursuri, ţinând seminarii, pregătind studenţi, nu prea are cum să fie mută. Şi, cu atât mai mult, ca ziarist de presă scrisă şi de radio. Urmărind însă transcrierile interviurilor luate de ea unor personalităţi din aproape toate domeniile, îţi dai seama că, departe de a fi taciturnă, Irina Airi...
Crises present significant challenges for organizations. But, while critical events are inevitable, not every business is sufficiently equipped for when things don’t go according to plan. This book focuses on business under crisis conditions, along with organizational responses and adaptation. Adaptation can be seen as a learning process. It encompasses meaningful ways that help companies sustain their viability over the long term. Companies that respond quickly, often achieve more than just surviving. Some organizations will learn from a crisis, develop reactive resilience, and emerge stronger from the period of turbulence. They will be able to explore possibilities and create new pattern...
This book examines businesses under crisis conditions through a composition of contextual accounts. The Editors argue that crises are transformative, evolutionary and even revolutionary in the development of organizations, industries and markets. Moreover, crises reform the context in which organizations operate, including customers and their behaviour. As such, they need to be viewed as conduits to change, accelerators of evolution and catalysts of innovation in organizations. Emphasising the importance of ‘context’ and its complexities, the book argues that for crisis, as a concept and notion, context is crucial to any understanding of the meaning that should or could be attached to it...
En este libro confluyen algunas de las búsquedas en filosofía, lenguaje y educación que persiguen los investigadores de la Facultad de Filosofía y Letras de la Universidad Santo Tomás de Colombia. Por el camino de la filosofía, se hallarán acercamientos a la poesía en Platón, a la escritura en Benjamin y a la religión en Rosenzweig y Ricoeur. Por el del pensamiento latinoamericano, se hallarán estudios de historia de las ideas y políticas de la dialéctica entre poder y democracia. Por el del lenguaje, se estudiará la mística de Josefa del Castillo, a Santiago Gamboa y la pragmática discursiva del fútbol. Y por el pedagógico, se verán las rutas del aprendizaje autónomo en la universidad.