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Beyond Borders: Myotonic Dystrophies – A European Perception
Myotonic dystrophies (DMs) are pleotropic multisystemic diseases. These dominantly transmitted repeat disorders affect multiple organs of the human body at all ages – from the newborns to the elderly. The present Research Topic represents a timely addition to the expanding body of evidence which aims to provide novel perspectives in our understanding of myotonic dystrophies. This collection of original contributions and standpoint reviews from multiple leading DM centres in Europe describes the state of the art for the characterization of the DMs diseases, the development of molecular strategies to target its multisystemic nature, and provides evidence of screening and testing novel therapeutic avenues.
Chocolate as Medicine
The Mesoamerican population who lived near the indigenous cultivation sites of the "Chocolate Tree" (Theobromo cacao) had a multitude of documented applications of chocolate as medicine, ranging from alleviating fatigue to preventing heart ailments to treating snakebite. Until recently, these applications have received little sound scientific scrutiny. Rather, it has been the reputed health claims stemming from Europe and the United States which have attracted considerable biomedical attention. This book, for the first time, describes the centuries-long quest to uncover chocolate's potential health benefits. The authors explore variations in the types of evidence used to support chocolate's ...
Congenital Heart Disease and Adolescence
This book provides medical care givers with detailed information on those aspects of adolescence that are of significance in the setting of congenital heart disease (CHD), from anatomic and physiologic changes to behavioral issues. In addition, it explains how care should be organized in order to ensure that the needs of adolescents with CHD are fully met. Both theoretical and practical aspects of the switch from a pediatric to an adult health perspective in CHD patients are outlined in detail, drawing attention to the importance of a structured transition plan and other best practices. As the survival of children with complex CHD improves further, the number of adolescents with CHD will continue to grow. Awareness of the challenges that these patients face is essential if they are to be appropriately prepared to assume adult roles and functioning. Readers will find Congenital Heart Disease and Adolescence to be an excellent source of relevant knowledge and guidance. It has been written for a broad audience, bearing in mind that care in adolescents is an interdisciplinary task involving close collaboration among physicians, specialists, nurses, patients, and relatives.
Cardiac Catheterization for Congenital Heart Disease
The second edition of this handbook is an up-to-date guide to the application of catheter-based interventions across the entire age range of congenital heart disease patients, from fetal life through to adulthood. It considers the changes and improvements that have occurred during the last few years in terms of new procedures, new tools and devices (in particular in the field of valves), new imaging and pre-procedural strategies, such as 3D-printing, 3D- rotational angiography and fusion imaging. It provides readers with clear instructions on techniques for vascular access, valve dilatation, angioplasty, stent implantation, defect closure, defect creation, pulmonary valve implantation and on...
Chaucer and the Making of Optical Space
The author links Chaucer's writings with the medieval optical tradition in its various forms (scholastic texts, encyclopedias, exempla, vernacular poetry) both in general cultural terms and through the discussion of specific examples. He shows how the science of optics, or perspectiva, provides an account of spatial perception, including visual error, and demonstrates how these aspects of optical theory impact on Chaucer's poetry. He provides detailed and sustained analysis of the spatial content of narratives across the range of Chaucer's works, relating them to optical ideas and making use of Lefebvre's theory of the production of space. The texts discussed include the Book of the Duchess, House of Fame, Knight's Tale, Miller's Tale, Reeve's Tale, Merchant's Tale, Squire's Tale and Troilus and Criseyde.
Piers Plowman and the Problem of Belief
"Piers Plowman is one of the greatest poems of Middle English. In this study Britton F. Harwood considers it as an expression of a crisis of faith and, as such, a landmark in the theological and philosophical history of the medieval era." "Harwood shows how the protagonist of the poem represents himself as one in need of a knowledge of Christ as present and existing. This kind of knowledge was elaborated in late thirteenth- and fourteenth century thought as 'notitia intuitiva': the poet wants, not a report of Christ, but Christ as an object of perception. Any conversion for him is consequent upon the vision of God. The action of the poem, then, consists in the poet's testing of certain human...
