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Written for health professionals and managers involved in the planning or provision of stroke care, this book provides a comprehensive, state-of-the-art overview of the evidence and practices that underpin high quality stroke care. It sets the scene by describing the epidemiology, trends and needs of stroke patients, followed by chapters on the prevention of stroke, investigation and management of TIAs (transient ischaemic attack), early management and thrombolysis, clinical management of acute stroke patients and rehabilitation. Each chapter is thematically-linked and provides a complete, up-to-date review of evidence, its implications for clinical practice, proven multidisciplinary models ...
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Stroke remains one of the most devastating diseases in industrialized countries. Recanalization of the occluded arterial vessel using thrombolysis is the only causal therapy available. However, thrombolysis is limited due to severe side effects and a limited time window. As such, only a minority of patients receives this kind of therapy, showing a need for new and innovative treatment strategies. Although neuroprotective drugs have been shown to be beneficial in a variety of experimental stroke models, they ultimately failed in clinical trials. Consequently, recent scientific focus has been put on modulation of post-ischemic neuroregeneration, either via stimulation of endogenous neurogenesi...