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Green Synthesis of Nanomaterials: Cytotoxicity and Drug Delivery
Over the past few decades, the increasing requirement for green chemistry and nanotechnology led to the adoption of green synthetic routes for the synthesis of nanomaterials using plants, microorganisms, and others. Hence, the green synthesis of nanomaterials has been considered by researchers through an eco-friendly path, which has led to much research in recent years on the synthesis of nanomaterials using plants as a non-toxic, cost-effective, accessible, easy, and environmentally friendly synthetic pathway. Synthesized nanomaterials through green chemistry are non-toxic and can be a good choice for medical applications such as drug delivery, imaging, biotechnology, and biomedical. In the...
Antibiofilm Strategies
Bacteria and fungi are able to aggregate together or on surfaces in densely packed microcolonies, facilitated by extracellular polymeric substances for cell protection and stability. These biofilms have proven to be extremely hard to eradicate and remove once established. In chronic infections, this condition can result in a high degree of morbidity and mortality as regular antibiotic treatments are ineffective against biofilms. In industrial facilities, the formation of biofilms can ruin production and result in enormous financial losses. In this book, the current state of antibiofilm research is presented by experts from around the world. Novel, cutting-edge techniques and new optimized st...
Renin-Angiotensin System
Exploring the contractile activity of smooth muscle segments isolated from various organs of healthy animals and animals with experimentally induced diabetes, she obtained original data about angiotensin II-induced force and time parameters. For the first time, she established the effect of ghrelin on angiotensin II-provoked contraction of the urinary bladder. Original data on the role of both types of angiotensin receptors for the contractile activity of the various segments of the gastrointestinal tract and bladder were obtained. By applying specific software for force and time parameter analysis, the contribution of different types of angiotensin receptors on muscle contractility has been shown. The new methodology was used to analyze the data obtained during the registration of smooth muscle relaxation activity, which allows the determination of not only the magnitude of the mechanical response but also the parameters related to the time and speed of the contractions. Plasma renin activity models have been developed using mathematical approaches to predict the effect of different drug doses on the behavior of the system.
Current Status of Natural Products Targeting Alzheimer’s Disease
Despite more than fifty years of intensive research on Alzheimer’s disease (AD) drug discovery, up till now only four medicines are approved by FDA for its treatment; among which three are acetylcholinesterase (AChE) inhibitors (donepezil, galantamine, and rivastigmine) and one is N-Methyl-D-aspartate (NMDA) antagonist memantine. These medications were launched during the initial research for AD but were not able to provide satisfactory results because of their limited efficacy and numerous side effects. The high-profile failure of late-stage clinical trials by prominent pharma firms for biomolecules that showed promising results in experimental models has added to the dissatisfaction of d...
Ovarian Cancer
By providing a comprehensive overview of current research findings, emerging therapies, and clinical practices, Ovarian Cancer: Disease, Diagnosis and Treatment is an invaluable resource. It will not only enhance the understanding of ovarian cancer's complex biology among professionals but also guide them in applying this knowledge to improve patient outcomes The book delivers the key knowledge and information needs faced by the audience center around understanding the latest advances in the underlying pathogenesis and treatment of ovarian cancer. This encompasses a broad spectrum of requirements, from grasping the molecular and genetic factors driving ovarian cancer development to staying u...
Phytoadaptogenic Properties of Medicinal Plants
Featuring traditional knowledge, the book Phytoadaptogenic Properties of Medicinal Plants offers an insight into diverse medicinal plants with their inherent phytotherapeutic characteristics. Since the prehistoric era, botanicals have been enlisted at the uppermost ladder in the survival of human existence. Though modern medicinal systems remain vital, at times of challenges or pandemics botanicals continue to serve as front liners, supporting people’s health and well-being by regulating the body’s inherent five defense systems such as angiogenesis, regeneration, DNA and epigenetics, microbiome, and immune system. The medicinal plants function as phytoadaptogens due to their intrinsic ab...
Handbook of 3D Printing in Biomedical Applications
3D printing is a promising fabrication technique capable of creating objects with precise structures and shapes based on 3D model data, allowing for versatile alterations and production of intricate shapes while also reducing the consumption of feedstock, particularly crucial in the cost-sensitive realm of medicine. In the biomedical sphere the use of 3D printing spans various applications, from artificial organs to sensors and orthopedic implants. This handbook explores the transformative role of technology in healthcare, focusing on materials, design, and innovation. It covers diverse applications like prosthetics, devices, tissue engineering, and medicine. This comprehensive resource high...
Spectroscopic Tools and Techniques for Analysis of Dental Materials
Spectroscopic Tools and Techniques for Analysis of Dental Materials: Current Trends introduces the dental materials and spectroscopic techniques applied for the analysis of such materials, including ceramic, metallic, polymeric and composites. The following individual chapters are primarily based on particular spectroscopic techniques and their applications, including X-ray Spectroscopy, Ultraviolet & visible spectroscopy, Fourier Transfer Infrared Spectroscopy, Raman Spectroscopy and Mass spectrometry. Different oral diseases, caries, calculus, periodontitis and oral mucosal diseases such as oral cancer, will be discussed as well.This is an ideal book for dental professionals, researchers and students interested in the analysis of dental materials. Key Features: Individual chapters include brief introductions of specific techniques Mathematical details are kept at a necessary minimum level Includes case studies to suit the target audience
Advances in Clinical Chemistry
Advances in Clinical Chemistry, Volume 110, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory
Nanopharmacology and Nanotoxicology: Clinical Implications and Methods
This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading
