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Liver diseases are seriously endangering human health in the world. In recent years, the incidence rate of liver disease is increasing year by year, and the age of patients tends to be younger. Therefore, it is urgent to find safe and effective drugs to treat liver diseases. The drugs used to treat liver diseases in clinic are mainly liver-protecting chemical drugs, some chemical synthetic drugs have serious problems, such as high toxicity, high recurrence rate, and high cost. However, medicinal and food plants have unique advantages in terms of safety and compliance, which have always been an important source for finding new hepatoprotective drugs. Importantly, new hepatoprotective natural ...
We are pleased to introduce the collection Frontiers in Chemistry – Medicinal and Pharmaceutical Chemistry Editor’s Pick 2024. This collection showcases the most well-received spontaneous articles from the past couple of years, and have been specially handpicked by our Chief Editors. The work presented here highlights the broad diversity of research performed across the section, and aims to put a spotlight on the main areas of interest. All research presented here displays strong advances in theory, experiment and methodology with applications to compelling problems. This collection aims to further support Frontiers’ strong community by recognizing highly deserving authors.
The book highlights the importance of prebiotics, probiotics and synbiotics in the signalling mechanism between gut microbiota and brain, also referred to as the gut-brain axis. A stable gut microbiota is essential for normal gut physiology and overall health, since it assists in proper signalling along the brain–gut axis. The book describes how the cross talks between gut microbiota and brain, not only regulate gastro-intestinal functions but also ensure proper functioning of cognitive behaviour and immunological functions. The various chapters describe probiotic microorganisms that colonize gastrointestinal tract and provide an array of health benefits to the host. It further elaborates about certain non-digestible oligosaccharides (prebiotics) are easily fermented by specialist microbes in the gut, to produce health-promoting metabolites and inhibit the growth of pathogenic bacteria. This book is useful for students, researchers and scientists in the field of microbiology, food science and nutrition. It is also meant for industry experts involved in developing nutraceuticals.
Biosurfactants are the surface-active biomolecules produced by microorganisms. Biosurfactants have gained commercial significance due to their unique properties, such as high surface activity, high specificity, low toxicity, tolerance to pH, temperature and ionic strength, biodegradability, excellent emulsifying and demulsifying ability, antimicrobial activity, ability to work under extreme conditions, and relative ease of preparation. Biosurfactants are used in several industries, including organic chemicals, petroleum, petrochemicals, mining, metallurgy (mainly bioleaching), agrochemicals, fertilizers, foods, beverages, cosmetics, pharmaceuticals and many others. The aim of this book is to...
Metal Oxides explores the multidimensional applications of metal oxides from nanostructured innovations to sustainable solutions. The book begins with the fundamentals of metal oxides, covering aspects such as their structure, synthesis techniques, characterization methods, and surface modification strategies. It expands into nanostructured metal oxide thin films, photocatalytic applications, nanocomposites for energy storage, and nanoengineering approaches to enhance surface reactivity. Sustainable development and environmental impact are also addressed, including green synthesis approaches, life cycle assessment, recycling and reuse strategies, and environmental applications for water purification and remediation. This book is intended for researchers and upper-level students studying materials science, chemistry, nanotechnology, and environmental science.
We are delighted to present the 2022 Edition of our Frontiers in Chemistry “Rising Stars” article collection. This collection showcases the high-quality work of internationally recognized researchers in the early stages of their independent careers. All Rising Star researchers were individually nominated by our Guest Editors and Chief Editors in recognition of their potential to influence the future directions in their respective fields. This year, we have selected Guest Editors who were featured as our Rising Stars in our previous collection together with Editorial Board members. The work presented here highlights the diversity of research performed across the entire breadth of chemical science and presents advances in theory, experiment and methodology with applications to compelling problems.
Neglected Tropical Diseases such as Chagas disease, leishmaniasis, tuberculosis, malaria, filariasis, and schistosomiasis affect over one billion people globally, particularly in low-income regions, and there is an urgent need for innovative therapeutic strategies. The integration of experimental and in silico methods has greatly accelerated the discovery and optimization of bioactive compounds from natural sources, providing insights into their mechanisms of action. Computational techniques allow researchers to screen large databases of synthetic for specific biological activities, while experimental methods validate these findings. This combined approach has revolutionized drug discovery a...
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