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Current Catalog
First multi-year cumulation covers six years: 1965-70.
IGFs in the Nervous System
In the last few years, considerable attention has been paid to the presence of insulin-like growth factors (IGFs) and their binding proteins (IGF-BPs) in the brain and peripheral neuronal tissue. IGFs are synthesized within the CNS, are bound to specific IGF-BPs and act on specific receptors. They represent a new class of growth factors and messengers in the brain and the periphery. Written by a group of outstanding experts in the field, the book provides an invaluable forum where important aspects of the production, regulation, biological actions, pathophysiological involvement, therapeutic applications for IGFs in many neurologic and neuromuscular disorders are addressed and critically evaluated.
Endocrinology
-- A complete, authoritative, up-to-date analysis of endocrine disease and basic endocrine physiology. -- Every aspect of endocrinology is covered in significant detail by an authority in the field. -- A clinical focus emphasizes diagnosis and therapy, with a brand new section on diagnostic methods and the pharmaceutical therapies used in treatment.
National Union Catalog
Includes entries for maps and atlases.
Biomarkers for Early Diagnosis of Alzheimer's Disease
Alzheimer's disease (AD) is characterized by the deposition into the brain of amyloid peptide, which originates a cascade of inflammatory events leading eventually to neuronal death. These pathological events likely occur several years before the clinical manifestation of the disease, implying that potential therapeutical interventions are currently started too late to give beneficial results. Recently, growing attention has been paid to the Mild Cognitive Impairment (MCI), considered the prodromal phase of AD, as 80% of subjects with MCI have been shown to develop AD within 5 years. Several studies aimed to identify biological markers to differentiate between normal aging and incipient AD h...
