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H.P. HIGER 1 In the seventeenth century people dreamed about a machine to get rid of evil spirits and obsessions, which were thought to be the main source of mis fortune and disease. I am not going to question this approach, because in a way it sounds reasonable. They dreamed of a machine that would display im ages from the inner world of men which could be easily identified and named. Somehow these are the roots of MR imaging. Of course, we now view disease from a different point of view but our objectives remain the same, namely to make diseases visible and to try to characterize them in order to cure them. This was the reason for setting up a symposium on tissue characterization. About 30...
The aim of this book is to present statistical problems and methods in a friendly way to radiologists, emphasizing statistical issues and methods most frequently used in radiological studies (e.g., nonparametric tests, analysis of intra- and interobserver reproducibility, comparison of sensitivity and specificity among different imaging modality, difference between clinical and screening application of diagnostic tests, ect.). The tests will be presented starting from a radiological "problem" and all examples of statistical methods applications will be "radiological".
Structure and Function of Membrane Proteins documents the proceedings of the International Symposium on Structure and Function of Membrane Proteins held in Selva di Fasano on May 23-26, 1983. This compilation makes it possible to obtain more information on the structure of membrane proteins, determining the structure in order to understand the function, and mechanism of action that is only understood by knowledge of the atomic structure. The gathering of data on the function of membrane proteins prior to knowledge of their structure is valuable for characterizing and defining the proteins. Once the structure is known, another stage of research will penetrate to the functional assignments of the structure. Other topics covered include the physical methods for the structure-function relationship; identification and mapping of sites in membrane proteins; and primary structure of transport proteins. Tertiary structure and molecular shape of membrane proteins and structure-function relationship in membrane proteins are also examined. This book is a good source of information for students and individuals conducting research on biochemistry, specifically on membrane proteins.
This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students.
Title Page -- CONTENTS -- PREFACE -- ASSESSMENT OF THE DIAGNOSTIC PERFORMANCE OF ECG COMPUTER PROGRAMS -- OBJECTIVE MEDICAL DECISION-MAKING: CLINICAL DATABASE FOR DIAGNOSIS OF JAUNDICE (EURICTERUS) -- OBJECTIVE MEDICAL DECISION MAKINGACUTE ABDOMINAL PAIN -- PROGNOSTIC VALUE OF AMBULATORY BLOOD PRESSURE -- CHEMICAL SENSORS FOR IN VIVO MONITORING -- OCULAR FLUOROMETRY: STANDARDIZATION AND INSTRUMENTATION DEVELOPMENT -- QUANTITATIVE ASSESSMENT OF OSTEOPOROSIS -- PET INVESTIGATION OF CELLULAR REGENERATION AND DEGENERATION -- ELECTRICAL IMPEDANCE TOMOGRAPHY APPLIED POTENTIAL TOMOGRAPHY -- AUTOMATION OF CYTOGENETICS -- BIOMAGNETISM: A DIAGNOSTIC TOOL -- NEW TECHNOLOGIES FOR COMMUNICATION IN THE HE...
This volume derives from papers presented at the 4th biennial meeting of the Italian Biophysical Society, held in Parma in October 1979. It includes review lectures presented by guest scientists (R.H. Adrian, E. Neher, S. Ottolenghi, and G. Zaccai); the remaining reviews and papers present some of the problems currently under study in our country. One can see that biophysical problems are studied under differ ent academic roofs, i.e., at physiological or biochemical departments. We consider this a strength and a weakness at the same time. The "Italian Bioenergetics Group" contributed to the success of the meeting, as much as the groups working in various laboratories of the Consiglio Nazionale delle Ricerche, in particular those of the National Group of Cybernetics and Biophysics. To them, and to the University of Parma, which contributed financial and organiza tional support, the Editors of this volume wish to express their appreciation. Particular thanks are to Drs. E. Carbone and V. Lenci, who spent time and effort for the meeting and in collecting the papers. The special care in the typing goes to the credit of Miss Rampello, to whom the Editors express their deepest gratitude.
Magnetic Resonance Spectroscopy in Biology and Medicine , presents the experimental and basic aspects of functional and pathological tissue characterization of MRS. A balance is drawn between the basic science, practical technologies and biomedical applications. Covering recent developments in the field: localization, 2D NMR, spectroscopic imaging, data quantification and quality assessment, as well as the basic principles of magnetic resonance spectroscopy, this book provides the lecturer and postdoctoral student, with a valuable research tool for the laboratory. This book is didactically-orientated, with 13 chapters devoted to MRS methodology, 3 chapters on MRS equipment, 13 chapters on clinical and experimental MRS, as well as an appendix containing the basic sciences for MRS and a MRS glossary.
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