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Reflections on a Century of Malaria Biochemistry
Malaria is one of the most common infectious diseases and an enormous public health problem. Each year it causes disease in approximately 650 million people and kills between 1 and 3 million, most of them young children in Sub-Saharan Africa. This book provides an overview of the research that has been done in malaria biochemistry in the quest to find a cure. It discusses how our understanding has helped us to develop better diagnostics and novel chemotherapies. Researchers will find having all of this information in one volume, annotated with personal reflections from a leader in the field, invaluable given the big push being made on various fronts to use the latest drug discovery tools to attack malaria and other developing country diseases. - Reviews the past 100 years of malaria biochemistry research providing researchers with an overview of the investigations that have been undertaken in this field - Chronicles both biochemical successes and failures
Dengue
This unique volume presents an up-to-date review of one of the world's major health problems -- diseases caused by the four dengue viruses. It begins with an insightful story of the origin of dengue disease outbreaks, including the emergence of severe and fatal dengue hemorrhagic fever. The nature, structure and biology of the four dengue viruses are described, and a major portion of the book is focused on the epidemiology of dengue as a mosquito-borne disease. This is complemented by critiques of existing mosquito control programs by three groups of outstanding authorities. The strongest element of the volume is its comprehensive description of the current understanding of dengue disease pathogenesis, followed by an analysis of the pros and cons of five of the most controversial areas in the field: the WHO DEF case definition, secondary dengue infections, virulent viruses, the role of abnormal T cells and autoimmunity.
Molecular Recognition in Host-Parasite Interactions
A very early step in microbial colonization and pathogenesis is that involving recog nition of the host by the microbe. In the final analysis such recognition is due to interaction between specific molecules on the two sides, without which host and microbe would ignore each other. It is therefore exciting to learn the rules that govern host-microbe interaction at to a large extent determines whether or not we are infected by the molecular level, which influenza virus, leishmanias, staphylococci and other pathogens. This book is a compendium of the addresses delivered at a symposium on molecular interaction at Porvoo, Finland in August 1991. Realizing that there are no a priori differ ences i...
Schistosomiasis
This volume brings together updated fundamental knowledge of the schistosomes, their biology and epidemiology, the mechanism of disease and a full description of the pathological sequelae and clinical syndromes in humans. It concludes with chapters on diagnosis and treatment prospects of vaccine development and the most significant controversies regarding immunology and epidemiology.
Tropical Medicine and Parasitology
Increased global travel has facilitated the spread of diseases that were previously restricted in their distribution. The fifth Edition of this internationally acclaimed book combines over 1,000 outstanding illustrations and expanded, authoritative text covering the clinical diagnosis, pathology and ecology of all recognized tropical and parasitic diseases.
Conn's Current Therapy 2000
The 2000 edition of "Conn's Current Therapy" continues the tradition of excellence with the most concise, up-to-date, easy-to-use source for recent advances in therapeutics. Includes information on state-of-the-art coverage of disorders affecting every organ system as well as the management of symptoms before a diagnosis is made.
