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Cancer Immunotherapy Principles and Practice, Second Edition
Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory proces...
The Basics of Cancer Immunotherapy
This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this...
Cancer Immunotherapy Principles and Practice
“Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for experienced scientists and clinicians looking to expand their knowledge base.”—Mario Sznol, MD, Professor of Medicine (Medical Oncology), Yale School of Medicine, New Haven, Connecticut “Given the important and exciting advances in cancer immunotherapy, it is not surprising that there is no dearth o...
Immunotherapy Approaches and Their Application in the Treatment of Cancer and Diabetes
Research Paper (postgraduate) from the year 2017 in the subject Medicine - Epidemiology, grade: 1.8, Egerton University, language: English, abstract: Immunotherapy approach seems to have gained a widespread application in the treatment of diseases, unlike in the past two decades when it was not considered as a significant treatment option. However, this treatment option dates back to the nineteenth century in which surgeons discovered the correlation between surgery and microbial infections, especially in post-surgery patients. For instance, William Coley, a renowned New York surgeon applied immunotherapy technique on cancer patients. This was after his realization that, some bacterial infec...
Immunotherapies for Allergic Disease
Get a quick, expert overview of the use of current and novel immunotherapies for use in the management and treatment of allergic reactions and diseases. This concise resource by Dr. Linda Cox covers the full range of allergic disease, including aeroallergens, asthma, food allergies, atopic dermatitis, and stinging insects. With essential coverage of allergen immunotherapies in addition to key topics on emerging allergen-associated immunomodulators, this succinct, comprehensive reference consolidates today's available information on this timely topic into a single convenient resource. - Discusses timely topics such as food tolerance, allergy, and allergen unresponsiveness; biologics for COPD and pediatric asthma; and adherence and pharmacoeconomics. - Summarizes practical guidelines and recommendations for use of immunotherapies in clinical practice. - Provides insight into the background and history of immunotherapies as a treatment for allergic disease. - Includes developments on the horizon, including alternative immunotherapy routes and modified allergens.
Immunotherapy of Cancer
This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunol...
Immunotherapies in Solid Tumors
This book covers state-of-the-art immunotherapeutic modalities also discusses how phenotypic plasticity of cancer cells plays a crucial role in the emergence of immune resistance. Targeting both medical oncologists and basic cancer researchers, this book fills a crucial gap by emphasizing the importance of a team medicine approach that integrates major medical centers and the clinical practices in their network. The goals are to educate professionals on the importance of an integrated approach to enhance the quality of research and patient care in oncology. This work stands out as an essential resource to the community challenged with integrating basic and translational research, along with clinical medicine in academic centers and their clinical networks worldwide. Authored by world-renowned experts in the field, this book fills a significant gap in the literature by focusing specifically on integrating the experience and expertise of basic scientists and clinicians both in academic centers and the oncology hospitals in their clinical network.
Unveiling the Tumor Microenvironment by Machine Learning to Develop New Immunotherapeutic Strategies (Volume I.B)
The tumor microenvironment (TME) plays a critical role in tumor proliferation, progression, and therapeutic responses. TME is a complex network of cancer cells, stromal cells, and, most importantly, infiltrating immune cells. Cancer cells regulate numerous biological functions through direct or indirect interaction with TME components. Emerging evidence suggests that TME crucially influences the response to both chemotherapy and immunotherapy. As scientific research has entered the big data era with the fast development of high-throughput sequencing technologies, machine learning has been gradually widely applied to extract important knowledge from big data bioinformatics. Thus, characterizing the TME landscape in cancer and identifying different immune-related TME phenotypes using machine learning-based bioinformatics analyses, in vitro experiments, and in vivo experiments are of great interest and significance.
Anaphylaxis and Hypersensitivity Reactions
Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.
