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Holism and the Evolving Cell
This book is unique in its identification of the homology between the atom and the cell, both of which exhibit deterministic and probabilistic traits, the cell using the atom as a ‘template’ for its emergence. Using mathematical algorithms, the author has connected the inorganic with the organic, in the attempt to bridge evolutionary biology with the underlying role of quantum mechanics.
Novel Aspects of PTHrP Physiopathology
The idea of this book is to attempt to provide an appropriate ground for the discussion of modern PTHrP-related issues, and for the consideration of attentive speculation and comments on current work. It is designed to intersect all the usual lines of disciplines, providing a site for presenting pertinent investigations and for discussing critical questions relevant to the entire field, thus seeking to develop a new focus and new perspectives for all those concerned with PTHrP and its pathobiology.
Self-Organization in the Nervous System
This special issue reviews state-of-the-art approaches to the biophysical roots of cognition. These approaches appeal to the notion that cognitive capacities serve to optimize responses to changing external conditions. Crucially, this optimisation rests on the ability to predict changes in the environment, thus allowing organisms to respond pre-emptively to changes before their onset. The biophysical mechanisms that underwrite these cognitive capacities remain largely unknown; although a number of hypotheses has been advanced in systems neuroscience, biophysics and other disciplines. These hypotheses converge on the intersection of thermodynamic and information-theoretic formulations of self...
Consciousness-Based Evolution
Consciousness is the key to understanding human existence. Many have attempted to determine the fundamental nature of consciousness based on deductive reasoning. In contrast to that, Consciousness-Based Evolution has exploited empiric evidence for the evolution of physiology from the unicell to man based on cell-cell communication as the origin of consciousness, each intermediary step representing an innate effort to maintain homeostasis by harnessing the energy flow initiated by The Big Bang. By tracing vertebrate evolution as development and phylogeny, focusing on specific emergent steps using a Bayesian approach, individual traits can be seen as exaptations of earlier ways in which existential threats were resolved over the course of evolution. You, the readers, are the beneficiary of those insights.
The 21st Century Singularity and Global Futures
This book introduces a 'Big History' perspective to understand the acceleration of social, technological and economic trends towards a near-term singularity, marking a radical turning point in the evolution of our planet. It traces the emergence of accelerating innovation rates through global history and highlights major historical transformations throughout the evolution of life, humans, and civilization. The authors pursue an interdisciplinary approach, also drawing on concepts from physics and evolutionary biology, to offer potential models of the underlying mechanisms driving this acceleration, along with potential clues on how it might progress. The contributions gathered here are divid...
Feeling and Knowing
'A truly awe-inspiring piece of writing' David Robson, author of The Intelligence Trap In recent decades, many philosophers and cognitive scientists have declared the question of consciousness unsolvable, but Antonio Damasio is convinced that recent findings in neuroscience, psychology and artificial intelligence have given us the necessary tools to solve its mystery. In Feeling & Knowing, Damasio elucidates the myriad aspects of consciousness and presents his analysis and new insights in a way that is faithful to our own intuitive sense of the experience. In forty-eight brief chapters, Damasio helps us understand the relation between consciousness and the mind; why being conscious is not th...
Pharmaceutical Inhalation Aerosol Technology, Third Edition
This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and cleara...
Quantum Mechanics, Cell-Cell Signaling, and Evolution
Quantum Mechanics, Cell-Cell Signaling, and Evolution offers a detailed accounting of the latest research and theorizing on the integration of quantum physics with biological action to produce a novel perspective on evolution. The book advocates for a paradigm shift towards understanding biology and medicine causally as predictive sciences, presenting quantum mechanics and physiology as vertically integrated. The author has taken a unique approach to the question of how and why evolution occurred. The account is based on extensive knowledge of lipid physical chemistry, and its role in the evolution of the lung under the influence of hormonal effects on structure and function. The title arran...
Hormones and Reality
Cellular-molecular approach to evolution has led to radical changes in our understanding of biologic principles ranging from the Cell, to the Life Cycle, Development, Homeostasis, Senescence/Aging, Heterochrony, Pleiotropy, Phenotype, and perhaps the purpose of life itself. Much of this new way of thinking about biology and medicine emanates from experimental evidence for epigenetic inheritance. This leads one to question whether our unicellular state is the actual primary level of selection. One particular system that is now recognized as being under the auspices of epigenetic inheritance is the endocrine system, which is conventionally thought to regulate physiologic homeostasis. However, ...
