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Platelets, Thrombosis and the Vessel Wall
Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, a
Nitric Oxide Synthase: Characterization and Functional Analysis
Although the function of nitric oxide in a regulatory capacity in the central and peripheral nervous system is widely recognized, the full scope of its actions and its interrelationships with other classes of regulatory molecules is just beginning to be comprehended. This volume contains a number of sophisticated and advanced methods essential for exploring the activity of nitric oxide in the brain. It will be a valuable tool for the established investigator and for those just entering the field. - Comprehensive protocols included for detection of NO and related compounds by chemical, immunohistochemical, and in situ hybridization techniques - Newly developed methods for the purification of neuronal and endothelial NO synthase, production of monoclonal antibodies to NO synthase, molecular cloning and expression of NO synthesis, and control of NO synthase gene expression - Assessment of NO-mediated functions in neurons, central nervous system, cerebral circulation, synaptic transmission, and vascular tone - Calcium imaging by confocal microscopy, evaluation of the effect of NO on iron metabolism, and detection of heme oxygenase-1 and -2 message level and distribution
Manual of Emergency Medicine
This manual, part of the best-selling Lippincott® Manual series is the most user-friendly quick-reference available in emergency medicine. In an easy-to-scan outline format with key terms boldfaced, the Manual of Emergency Medicine offers practical guidance for diagnosis and management of all types of emergencies. Lists of possible causes of symptoms lead readers rapidly to appropriate information. This edition is thoroughly updated, particularly those chapters focusing on drug therapy for infectious diseases, such as pneumonia or HIV.
Health Care Management: Principles and Practice
In an era of rapid advancements, "Healthcare Management" explores the transformative journey of modern healthcare. This book covers a broad spectrum of topics, from the evolution of healthcare systems around the world and the epidemiological perspectives of healthcare management to the intricate aspects of health policy, planning, and economics. The book examines emerging trends in healthcare needs assessment, public-private partnerships, and evidence-based medicine, offering critical insights into modern management practices. Healthcare reforms are discussed with a focus on professional regulation, law and ethics. Gain insights into the latest scientific discoveries and research methodologi...
Cecil Essentials of Medicine
For over twenty years, Cecil Essentials of Medicine has been a trusted and respected name in medicine. The new, 6th Edition carries on this legacy, laying the groundwork for effective diagnosis and treatment and encapsulating the core of internal medicine in an easy-to-read format. From recent developments in genetics and immunology to innovations in therapeutic approaches, readers will find concise coverage of today's best concepts and techniques. The smart way to study! Elsevier titles STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld ...
Harrison's Principles of Internal Medicine
Harrison's has defined internal medicine for millions of physicians and students worldwide since 1950. This Seventeenth Edition retains its balance of science and patient management and has been masssively updated to include an innovative array of new features and content. Beyond the expansion of an illustration program with more than 300 new, additional illustrations. The acclaimed "Approach to the Patient" and "Treatment" features have been redesigned to make referencing the content faster than ever before. Readers will find an expanded focus on global health, including a Global Advisory Board composed of 11 prominent medical experts from around the world and a chapter on Global Considerations in Medicine by Jim Kim and Paul Farmer. Also, the new chapter on the Epidemiology of Cardiovascular Diseases provides a uniquely valuable summary of this emerging global epidemic. A new Global Considerations icon identifies epidemiologic, diagnostic, and therapeutic distinctions betwe.
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Disorders of Hemoglobin
This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
