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Membrane Transport Mechanism
This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing numbers of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternati...
Chance in Evolution
The first book to synthesize scientific and philosophical work on chance, this edited volume brings together leading biologists, philosophers of science, and historians of science, who collectively explore the role that chance plays or doesn t play, as the case may be in evolution. The first part of the volume places chance in historical context and explores how Darwin, along with his contemporaries, understood chance in addition to its related concepts; how these various concepts changed as Darwin s theory of evolution by natural selection developed into the Modern Synthesis; and how the chanciness of Darwinian theory affected theological resistance to it. The second part explores the impor...
Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria
The discovery of antibiotics represented a key milestone in the history of medicine. However, with the rise of these life-saving drugs came the awareness that bacteria deploy defence mechanisms to resist these antibiotics, and they are good at it. Today, we appear at a crossroads between discovery of new potent drugs and omni-resistant superbugs. Moreover, the misuse of antibiotics in different industries has increased the rate of resistance development by providing permanent selective pressure and, subsequently, enrichment of multidrug resistant pathogens. As a result, antimicrobial resistance has now become an urgent threat to public health worldwide (http://www.who.int/drugresistance/docu...
Das Schweizer Buch
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DUZ Magazin
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Spirit of Resistance
The first book to offer a complete story of the extraordinary proliferation of Dutch clandestine literature under the Nazi occupation. Clandestine literature was published in all countries under Nazi occupation, but nowhere else did it flourish as it did in the Netherlands. This raises important questions: What was the content of this literature? What were the risks of writing, printing, selling, and buying it? And why the Netherlands? Traditionally, the combative Dutch "spirit of resistance" has been cited, a reaction not only to German oppression but to German propaganda: while the Germans hoped to build bonds with their "Germanic" Dutch "brothers," clandestine literature insisted on their...
The Ethics and Religious Philosophy of Etty Hillesum
The Ethics and Religious Philosophy of Etty Hillesum contains the proceedings of the second international Etty Hillesum Congress at Ghent University in January 2014 and is a joint effort by fifteen Hillesum experts to shed new light on the life, works and vision of the Dutch Jewish writer Etty Hillesum (1914-1943), one of the victims of the Nazi-regime. Hillesum’s diaries and letters illustrate her heroic struggle to come to terms with her personal life in the context of the Holocaust. This volume revives Hillesum research with a comprehensive rereading of her texts. With the current rise of interest in peace studies, Judaism, the Holocaust, inter-religious dialogue, gender studies and mysticism, it is evident that this book will be invaluable to students and scholars in various disciplines.
