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This book focuses on the envelope of Gram-positive bacteria including its composition, the latest discoveries in the mechanisms behind its assembly, and its role in pathogenesis. Furthermore, new applications in biotechnology and vaccine development involving these bacteria are discussed in detail. This concise volume consists of eleven chapters by prominent experts in the field, which review the latest findings and current state of knowledge on a range of diverse yet interlinked aspects. This book is written for all researchers, clinicians and technicians engaged in basic or applied science projects on Gram-positive bacteria.
This is the sixth set of Handbook of Porphyrin Science.This 5-volume set provides a comprehensive review of the most up-to-date research on porphyrin, heme and chlorophyll biochemistry, as well as applications to biomedicine and bio-inspired energy. In-depth coverage of topics along with perspectives on outstanding questions and future research directions by the authors make these volumes an essential resource for both beginning and advanced investigators in the field. It is also suitable for non-experts in porphyrin, who wish to have an overview of the fundamental discoveries and breakthroughs in the porphyrin arena related to medicine and bio-inspired energy.Bringing together the biochemistry of porphyrin-binding proteins and their clinical relevance and applications to medicine and renewable energy, this set provides readers with an integrated coverage of porphyrin biochemistry. At the same time, it challenges readers with new questions and perspectives of research regarding the role of porphyrin biochemistry in the future of medicine and renewable energy.
Streptococcus pneumoniae (the pneumococcus) is a commensal of the human nasopharynx during childhood, but also causes a variety of infections, such as otitis media (OM), pneumonia, bacteremia, and meningitis, mainly affecting infants, the elderly and immunocompromised patients. Pneumococcal pneumonia alone produces more child deaths, every year, than any other bacterial disease worldwide. To date, more than 90 distinct capsular serotypes have been identified. Current pneumococcal conjugate vaccines (PCV) protect against 7, 10 or 13 different pneumococcal types. These vaccines have decreased the burden of pneumococcal disease produced by vaccine types but provide poor protection against non-v...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.