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Computer-Aided Drug Design
This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
Fluoride and Fluorocarbon Toxicity
This book presents fluoride and fluorocarbon toxicity with respect to remediation and health issues. It covers sources of fluoride and fluorocarbon contamination, its impact on human health, and prospective remediation by multi-disciplinary approaches with the application of recent advanced technology. This book brings together a diverse group of researchers from different disciplines to address the challenges posed by global mass poisoning caused by fluoride and fluorocarbon contamination. The book sheds light on the global environmental issues and proposes solutions to contamination through multi-disciplinary approaches. The book contains three parts. The first part describes the different...
Groundwater Depletion and Sustainability
This contributed volume details how Artificial Intelligence (AI) and Earth observation systems can effectively improve the prediction of groundwater quality and support decision-making in arid and semi-arid regions. Earth observation systems, including remote sensing and geographic information systems (GIS), play a crucial role in assessing and monitoring groundwater quality. Remote sensing data, such as satellite imagery, can provide valuable information on land cover, vegetation indices, and water quality parameters. GIS tools enable the spatial analysis and visualization of groundwater quality data. AI and Earth observation-based methods support effective water resource management by iden...
Methods in Fungal Biology: A manual of Laboratory Protocols
Fungi are one of the important components in the biosphere, ubiquitous in nature and essential in recycling of nutrients in all type of habitats. These organisms play key role as decomposers, phytopathogens, symbionts and in elemental cycles. Despite of their important roles in the biosphere, it is important to explore all categories of fungi. This manual is designed to provide detailed information on methods of fungal isolation and identification from various substrates. The book is comprised in three parts where first part contains information about instrumentation, techniques, stains, cultures and reagents; second part describe about fungal isolation and identification while, third part d...
Climate Change and Environmental Issues
Climate change is one of the greatest challenges of the 21st century. Climate is changing across our planet, largely, as a result of human activities. The indicators of climate change include physical responses such as changes in the surface temperature, atmospheric water vapour, severe climatic events, melting of glaciers, and a rise in sea level. Mountain ecosystems being exceptionally fragile are prone to both natural and anthropogenic drivers of change, which ranges from volcanic and seismic events and flooding to global climate change and of vegetation and soils, resulting from inappropriate agricultural and forestry practices and extractive industries. Environmental issues directly aff...
Comprehensive Laboratory Manual of Life Sciences
The present book ‘Comprehensive Laboratory Manual of Life Science’, deals with practical trends in modern biological sciences. It furnishes protocols on recent advances in biotechnological methods and aims to cover three most important aspects of this interdisciplinary stream; such as Microbiology, Biochemistry and Molecular biology. The book contains four sections: 1. Introduction: emphasizes on good laboratory practices and etiquettes for beginners; the do’s and don’ts of working in a laboratory, concepts and terminology, etc. 2. Instruments: Principle and Precautions: explores commonly used equipments employed in different experiments. 3. Experiments: is further divided into three...
Advances in Biotechnology
The book “Advances in Biotechnology” is about recent advances in some of the important fields that are ongoing in certain biotechnological applications. Biotechnology has been quite helpful in keeping pace with the demands of every increasing human population and in improving the quality of human life. Major biotechnological achievements associated with human welfare have been from the fields like genetic engineering; transgenic plants and animals; genomics, proteomics, monoclonal antibodies for the diagnosis of disease, gene therapy etc. Fourteen authoritative chapters written by experts having experience in academics and research on current developments and future trends in biotechnolo...
Laboratory Manual of Microbiology, Biochemistry and Molecular Biology
Though many practical books are available in the market but this Laboratory Manual of Microbiology, Biochemistry and Molecular Biology is an unique combination of protocols that covers maximum (about 80%) of the practicals of various Indian universities for UG and PG courses in Bioscience, Biotechnology, Microbiology, Biochemistry and Biochemical Engineering.
