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Biosafety Assessment of Probiotic Potential
This volume provides methods on procedures for assessing the biosafety aspects of probiotics. Chapters are divided into five parts detailing in vitro biosafety assessment, biogenic amine production, D-lactic acid production, toxin production, production of various enzymes, determination of toxicity, mutagenicity, virulence genes, capsule formation, hemolytic activity, DNAse activity, bile salt deconjugation, antibiotic resistance, antibiotic resistance gene transfer, mucin degradation, platelet aggregation, and in vivo biosafety assessment of probiotics including determination of infectivity, reproductive and developmental toxicity, and evaluation of immunological parameters in animal models. Authoritative and cutting-edge, Biosafety Assessment of Probiotic Potential aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Microbial Symbionts
Microbial Symbionts: Functions and Molecular Interactions on Host focuses on microbial symbionts of plants, animals, insects and molecular methods in the identification of microbial symbionts. The book describes the molecular mechanism and interactions of symbiosis of microbiome in plants, animals and humans. It brings the latest techniques for identification, localization and functional characterization of host-associated microbes and explains the role/importance of microbial symbionts. This comprehensive reference covers a wide range of symbiotic microorganisms used for basic and advanced techniques associated with the isolation, characterization and identification of microbial symbiotic m...
Autoimmunity
Autoimmunity is defined as an immune response against a self-antigen. This abnormal immune response can lead to tissue damage and to the development of autoimmune disease. From organ-specific autoimmune diseases, such as myasthenia gravis, to non-organ-specific, such as systemic lupus erythematosus, autoimmune diseases represent a heterogeneous group of disorders which affect approximately 6% of the population. The pathogenesis of many autoimmune diseases is complex and remains not completely understood. The aim of this book is to present current knowledge regarding pathogenic mechanisms of autoimmune diseases, clinical aspects of specific autoimmune diseases, like vitiligo, celiac disease and autoimmune liver disease, as well as insights regarding specific therapies.
Probiotics against Antimicrobial Resistance
This book provides an overview of antimicrobial resistance (AMR), including its underlying causes, mechanisms, global ramifications, and the potential of probiotics as a viable approach in combating AMR. It explores the potential of probiotics to counteract resistance by competing with pathogenic bacteria, modulating the immune system, and producing antimicrobial compounds. It also examines the applications of probiotics in biofilm-related infections, respiratory health, urinary tract infections, and oral health. Additionally, the book covers important considerations such as safety, regulatory frameworks, challenges, and risks associated with probiotics in AMR. It provides insights into the ...
염증 해방
암, 비만, 아토피, 심장질환, 당뇨, 관절염, 우울, 치매…… “당신의 병은 모두 ‘염증’ 때문에 시작되었다!” 암, 심장질환, 당뇨, 관절염, 치매는 백세 시대를 살아가는 데 있어 인류에게 가장 위협이 되는 다섯 가지 대표 질병이다. 이 질병들은 증상도 치료법도 다양하지만 이들을 관통하는 단 하나의 단서가 있다. 모두 염증에서 시작되었다는 것. 초기 발생한 염증을 제때 잡지 못했고, 결국 생명까지 위협하는 거대 질병으로 키워 온 것이다. 우리는 작은 병에 관대하고 작은 병은 당신의 이런 속내를 간파하고 있다. 이런데...
Probiotics in The Prevention and Management of Human Diseases
Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, ...
Regulatory T cells and Autoimmune Diseases
Regulatory T cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic aspects. In particular, this book deals with the various Treg based mechanisms which can lead to autoimmune diseases and covers the different aspects of linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies. The book specifically focuses on the Treg based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood & blood vessel, and eye diseases and aims to provide a mus...
Anticancer Immunity: Reviewing the Potential of Probiotics
Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Anticancer Immunity: Reviewing the Potential of Probiotics explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies. This volume consists of 11 chapters. The volume continues from the previous entry with chapters focused on probiotics’ anticancer immunity in specific cancers such as, bladder cancer, renal cell carcinoma, prostate cancer, lymphomas, pancreatic cancer, oral cancer and oropharyngeal cancers. The bo...
Probiotics in Anticancer Immunity
Probiotics have been suggested to be involved in both prevention and treatment of various human cancers. Probiotics in Anticancer Immunity explains biochemical mechanisms of anticancer immunity exerted by probiotics in various human cancers. It presents edited chapters focused on the evidence of probiotic use against human cancers through several animal and human studies. Part 1 of Probiotics in Anticancer Immunity consists of 11 chapters. The introductory chapters provide information about the link between gut microbiota and the host immune system in cancer and the general mechanisms of anticancer immunity exerted by probiotics. Subsequent chapters are focused on probiotics’ anticancer im...
