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This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including: host-pathogen interactions causal relationships between genes and the environment the effects of environmental chemicals on gene expression DNA methylation The book also covers the analysis and provides models for understanding the epigenetics-pathology connection. This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.
This book discusses globalization and its impact on human health. The population of the world grew from 1 billion in 1800 to 7 billion in 2012, and over the past 50 years the mean temperature has risen faster than ever before. Both factors continue to rise, as well as health inequalities. Our environment is changing rapidly, with tremendous consequences for our health. These changes produce complex and constantly varying interactions between the biosphere, economy, climate and human health, forcing us to approach future global health trends from a new perspective. Preventive actions to improve health, especially in low-income countries, are essential if our future is going to be a sustainabl...
This volume is a serious attempt to open up the subject of European philosophy of science to real thought, and provide the structural basis for the interdisciplinary development of its specialist fields, but also to provoke reflection on the idea of ‘European philosophy of science’. This efforts should foster a contemporaneous reflection on what might be meant by philosophy of science in Europe and European philosophy of science, and how in fact awareness of it could assist philosophers interpret and motivate their research through a stronger collective identity.The overarching aim is to set the background for a collaborative project organising, systematising, and ultimately forging an identity for, European philosophy of science by creating research structures and developing research networks across Europe to promote its development.
Research on the relationship between health and the environment in a postgenomic context is increasingly aimed at understanding the various exposures as a whole, simultaneously taking into account data pertaining to the biology of organisms and the physical and social environment. Exposome research is a paradigmatic case of this new trend in environmental health studies. This book takes a multidisciplinary approach focusing on the conceptual, epistemological, and sociological reflections in the latest research on environmental and social determinants of health and disease. It offers a combination of theoretical and practical approaches and the authors are scholars from a multidisciplinary background (epidemiology, geography, philosophy of medicine and biology, sociology). Crucially, the book balances the benefit and cost of the integration of biological and social factors when modelling aetiology of disease.
Revised and expanded, this edition provides comprehensive coverage of occupational health and safety. A new CD-ROM version is available which provides the benefits of computer-assisted search capabilities
Methods, just as diseases or scientists, have their own history. It is important for scientists to be aware of the genesis of the methods they use and of the context in which they were developed. A History of Epidemiologic Methods and Concepts is based on a collection of contributions which appeared in "SPM International Journal of Public Health", starting in January 2001. The contributions focus on the historical emergence of current epidemiological methods and their relative importance at different points in time, rather than on specific achievements of epidemiology in controlling plagues such as cholera, tuberculosis, malaria, typhoid fever, or lung cancer. The papers present the design of prospective and retrospective studies, and the concepts of bias, confounding, and interaction. The compilation of articles is complemented by an introduction and comments by Prof. Alfredo Morabia which puts them in the context of current epidemiological research.
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This text presents scientific inquiry into the causes of environmental and occupational disease, and the means of reducing the toll of illness and death from environmental agents. The preventive strategies discussed include identifying agents causing disease, determining exposure to them, setting priorities for change based on risk assessment, educating citizens and workers, and regulatory approaches.
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