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Cancer Nanotechnology
Cancer nanotechnology is a growing, emerging area of cross-disciplinary research that aims to develop efficient, specific and noninvasive approaches to restore the health and well-being of all cancer patients through more effective diagnosis and treatment. This new volume serves as a fundamental guide to cutting-edge topics in cancer nanotechnology, including advances in therapy, the use of nanoparticles and nanomaterials, future directions for nanocarriers in cancer therapy, and the application of DNA and RNA nanovaccines. Organized into four sections, the volume presents an overview of research and innovation in the emerging field of nanotechnology as a powerful tool in the diagnosis, imaging and treatment of cancer. International experts author chapters addressing targets of cancer therapy, materials for cancer nanotechnology, strategies for cancer therapy using nanotechnology, and innovative nanotechnologies for cancer diagnosis and treatment. The volume will be useful for a broad audience, including cross-disciplinary researchers, trainees, health professionals, and experts in industry.
Endocytosis and Signaling
This book focuses on the context dependency of cell signaling by showing how the endosomal system helps to structure and regulate signaling pathways. The location and concentration of signaling nodes regulate their activation cycles and engagement with distinct effector pathways. Whilst many cell signaling pathways are initiated from the cell surface, endocytosis provides an opportunity for modulating signaling networks’ output. In this book, first a series of reviews describe the endocytic and endosomal system and show how these subcellular platforms sort and regulate a wide range of signaling pathway components and phenotypic outputs. The book then reviews the latest scientific insights into how endocytic trafficking and subcellular location modulate a set of major pathways that are essential to normal cellular function and organisms’ development.
Nanoparticles in Cancer Therapy
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...
Artificial intelligence in predicting, determining and controlling cell phenotype or tissue function in inflammatory diseases
The last decade has seen rapid development in the use of computational techniques at bulk tissue and single-cell level. However, our knowledge remains limited in this regard, and further progress is needed, especially in inflammatory and degenerative diseases. Controlling, modeling, or predicting cellular phenotype in this context using artificial intelligence (AI) will greatly improve the available in vitro, in situ, in vivo, and in silico methods, but also aid in the understanding of disease pathology and therapeutic efficiency. These methods not only have ramifications for our pathophysiological understanding of tissue function but are also important for advancing AI methods in cell culture, tissue explants, or in vivo for immunologically relevant characteristics of single cells, cell populations, and tissues to predict cell or tissue function.
Novel Molecular Oncotargets and Nano-Oncotherapeutics
This book describes the latest findings related to tumor molecular microenvironment and its involvement in cancer progression. It includes authoritative articles on recent progress in the field based on the current results of apoptosis, autophagy, and tumor signaling highlight new cancer targets for therapeutic manipulation as a strategy of cancer control. It explores the advancements of molecular mechanisms in oncology to identify new therapeutic, prognostic, and diagnostic targets in the molecular events of neoplasia. Recent data on nanoformulations in the book for the therapeutic management of various types of cancer indicate a revolutionary change in cancer therapy in the near future. The primary audience of this book is students and faculties from academic institutions, the researchers, scientists, clinicians, and scientists belong to the research and development wing in industries, as the book provides the latest data and findings in the described areas as a valuable source of incredible information in the field in an organized manner.
