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Given the success of the previous collection, The Complex Phenotype of Diabetic Cardiomyopathy: Clinical Indicators and Novel Treatment Targets, and new advances in the field, we are pleased to announce the launch of Volume II. Diabetic cardiomyopathy is a clinical condition characterized by heart dysfunction that develops in diabetic patients in the absence of hypertension and coronary atherosclerosis. Key features include myocardial fibrosis, cardiac stiffness, left ventricular hypertrophy, and decreased left ventricular compliance, which eventually progress to heart failure with reduced ejection fraction. To detect changes in cardiac structure and function, such as fibrosis, various nonin...
Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area. This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part ...
This Research Topic is part of a series with: Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds Chronic inflammation is a component of many disease conditions that affect a large group of individuals worldwide, which is characterized by persistent, low-grade inflammation and is increased in the aging population. It occurs when an initiating stimulus is not removed or if the resolution process is disrupted, resulting in a state of low-grade inflammation. It is acknowledged that chronic inflammatory diseases are involved in cardiovascular diseases, endocrine disease, neurodegenerative disease, hepatic disease, pulmonary disease, gastrointestinal ...
An effortless—really!—approach that turns the body into a fat-burning machine. Is it possible to eat well, drink wine, and still lose weight? Melanie Avalon is living proof that, heck yeah, it’s not only possible, it’s unbelievably simple and straightforward. It’s all about the what (mostly Paleo, but she’s not a monster about it), the when (believe it or not, brief fasting can mean freedom rather than restriction), and the wine (red wine can be a secret bullet for weight loss—who knew?). It’s a combination that Avalon discovered after years of self-experimentation and intense research on the mechanics of body fat regulation. In What When Wine, Avalon shares her journey to a healthier lifestyle, with the tips and tricks she learned along the way, as well as a jumpstart plan including 50 delicious Paleo-friendly, gluten-free recipes by chef Ariane Resnick.
Diabetic cardiomyopathy is a clinical condition of heart dysfunction that develops in the absence of hypertension and coronary atherosclerosis in diabetic patients. The main characteristics of diabetic cardiomyopathy are myocardial fibrosis, cardiac stiffness, left ventricular hypertrophy and decreased left ventricular compliance. This eventually progresses to clinical heart failure with reduced ejection fraction. To detect changes in cardiac structure and function, such as fibrosis, several noninvasive techniques have been used. These include echocardiography, cinematic magnetic resonance imaging, and computed tomography. From a mechanistic perspective; oxidative stress, inflammation, enhan...