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This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
In recent years, the importance of the tissue surrounding a tumour, commonly termed the tumour microenvironment (TME), has been increasingly recognized. Whilst likely to play a tumour-suppressive role in the early stages of carcinogenesis, a wide array of evidence indicates the TME becomes corrupted by the presence of malignant cells and becomes tumour permissive, promoting growth, metastasis, immune evasion and therapeutic resistance. The major components of the TME are fibroblasts, immune cells, endothelial cells and the extracellular matrix in which they are embedded, but this is highly heterogeneous and site-specific, with other cells such as adipose, bone and neuronal likely to play a p...
Buku penyakit Jaringan Lunak Rongga Mulut yang berada di tangan pembaca ini disusun dalam 18 bab, yaitu : Bab 1 Anatomi Rongga Mulut Bab 2 Jaringan Penyangga Gigi Bab 3 Kelenjar Liur Bab 4 Gangguan Perkembangan Lidah Bab 5 Tumor Rongga Mulut Bab 6 Sialolithiasis Bab 7 Mucocele dan Ranula Bab 8 Kista Odontogen Rongga Mulut Bab 9 Lesi Jinak Rongga Mulut Bab 10 Stomatitis Aphtous Recurrent (SAR) Bab 11 Leukoplakia Bab 12 Erithroplakia Bab 13 Actinic Cheilitis Bab 14 Oral Lichen Planus Bab 15 Eritema Multiformis Bab 16 Squamous Cell Carsinoma (SCC) Bab 17. Penyakit Gingiva Bab 18. Terapi Penyakit Jaringan Lunak Rongga Mulut