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Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.
One of the most exciting developments in biological sciences has been their merging with chemistry and physics resulting in the new disciplines of biochemistry, biophysics and molecular biology. As the developments of these new disciplines has been so rapid many of the key discoveries have occurred within the life-time of a number of prominent scientists in the field. The chapters in this and in future volumes are meant to complement with personal recollections by these scientists, the History of Biochemistry in this series (vols. 30-33 by M. Florkin and Vol. 34 by P. Laszlo). These bibliographic and autobiographic chapters convey to the reader lively, albeit at times subjective, views on both the scientific and social environments of the authors. The editor cosidered it presumptuous to give the authors narrow guidelines or to suggest changes in the chapters he received. The contributions assembled in this volume will convey the flavour of each author's particular personality.
No detailed description available for "Flavins and Flavoproteins 1987".
No detailed description available for "Flavins and Flavoproteins 1990".
The dynamic field of flavin and flavoprotein biochemistry has seen rapid advancement in recent years. This comprehensive two volume set provides an overview of all aspects of contemporary research in this important class of enzymes. Topics treated include flavoproteins involved in energy generation, signal transduction and electron transfer (including respiration); oxygen activation by flavoproteins; the biology and biochemistry of complex flavoproteins; flavin and flavoprotein photochemistry/photophysics as well as biotechnological applications of flavoproteins. Recent developments in this field include new structures (including those of large membrane-integral electron transfer complexes containing FMN or FAD), elucidation of the role of flavoproteins in cell signalling pathways (including both phototaxis and the circadian cycle) and important new insights into the reaction mechanisms of flavin-containing enzymes. This volume focussing on oxidases, dehydrogenases and related systems is an essential reference for all researchers in biochemistry, chemistry, photochemistry and photophysics working on flavoenzymes.
This publication, a collection of 174 papers, encompasses the fundamental and intricate photochemistry and electron transfer of flavins and flavoproteins, the mechanisms associated with enzymes utilising flavins (such as dehydrogenases, reductases, oxidases, monooxygenases, synthases, peroxidases), the three-dimensional structures of flavoproteins and flavoenzymes and the emerging role of flavins and flavoproteins in medicine. Flavins and Flavoproteins 1996 continues the series which has appeared every three years since 1965. Presented are overviews of key areas of flavin research, coupled with the most recent understanding of the chemistry/photochemistry of flavins and the structure/functio...
As a scientist with an interest in proteins you will, at some time in your career, isolate an enzyme that turns out to be yellow—or perhaps you already have. Alternatively, you may identify a polypeptide sequence that is related to known flavin-containing proteins. This may, or may not, be your first encounter with flavoproteins. However, even if you are an old hand in the field, you may not have exploited the full range of experimental approaches applicable to the study of flavoproteins. We hope that Flavoprotein Protocols will encourage you to do so. In this volume we have sought to bring together a range of experimental methods of value to researchers with an interest in flavoproteins, ...
"Comprehensive world directory of establishments conducting research in the medical and biochemical fields." Includes approximately 100 countries. Entries are arranged under countries in alphabetical order. Contains a chapter on international organizations. Each entry gives such information as address, products, affiliation, and number of graduate research staff. Titles of establishments and subject indexes.