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The exocrine pancreatic function can be impaired by many different pancreatic disease as well as diseases that do not appear to be directly linked to the exocrine pancreas. Hormones stimulating exocrine function (e.g. CCK) might be reduced in diseases affecting the intestinal mucosa (IBD, celiac disease, AIDS) resulting in decreased exocrine secretion. The function of digestive enzymes might be affected by post-cibal asynchrony or by a decreased intraduodenal pH as in Zollinger-Ellison syndrome (ZE). An atrophy of pancreatic tissue might be caused by a lack of trophic factors, as may occur in IDDM, and pancreatic damage might occur due to drugs used for the treatment of other diseases. While...
Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities. This new fifth edition is an update and expansion of the rapid clinical and scientific advances in improving prognosis, and the impact of COVID-19, all of which has transformed conventional models of care. It covers basic science, such as how detailed understanding of the biology of the CFTR gene and protein has led to novel and beneficial therapies, as well as all aspects of clinical management in high-, middle- and low-income settings and the voices of individuals with CF from acros...
Treatment & Prognosis in Pediatrics provides paediatricians with recent advances in the successful management of sick children, with emphasis on understanding the characteristics of a disease and how different treatment options may influence it. Presented in an easy to ready format, each section discusses diseases and disorders found in a different part of the body. A separate chapter is dedicated to neonatal disorders. Each chapter begins with an initial description of the disease, its pathology and epidemiology, followed by an evaluation of different treatment options and prognosis. Tables and lists summarise diagnostic and therapeutic information and further reading suggestions are offered in each chapter. Key points Presents recent advances in treatment and prognosis of sick children Covers diseases and disorders in all parts of the body Separate chapter dedicated to neonatal disorders Includes tables, lists and further reading suggestions
This book is a comprehensive guide to all aspects on paediatric intensive care. The fourth edition has been fully revised to include the latest guidelines and advances in technology. The extensive text of 1200 pages explains practical and surgical issues, with thorough coverage of respiratory and cardiac care. Other conditions specific to different systems of the body are also discussed – endocrine, gastrointestinal, neurological and more. Several chapters are dedicated to environmental injuries including burns, electric shock, heat disorders, near-drowning, and poisoning. The book concludes with discussion on psychosocial issues, ethical and medicolegal aspects, training, research, quality improvement, and use of therapeutic drugs in paediatric intensive care. The text is highly illustrated with clinical photographs, diagrams and flowcharts. Key points Comprehensive guide to all aspects of paediatric intensive care Fully revised fourth edition featuring latest guidelines and technological advances Extensive text of 1200 pages further enhanced by clinical photographs, diagrams and flowcharts Previous edition (9789351527398) published in 2015
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Principles and Practice of Pediatric Neurosurgery, Third Edition is a completely revised edition of the most authoritative guide to the management of pediatric neurosurgical disorders encountered in clinical practice. Written by leaders in the field, it provides pediatric neurosurgeons with a clear understanding of the current standards of practice and treatment in the subspecialty. Key Features: Now in full color, with more than 1,000 images An increased emphasis on clinical management strategies in pediatric neurosurgery Seven new chapter topics, including cellular therapy for pediatric neurosurgical disease, conjoined twins, lipomeningoceles, and skeletal syndromes Pearls and pitfalls in every chapter This book is an essential reference for all residents and practitioners in pediatric neurosurgery and pediatric neurology.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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