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Synbiotics in Human Health: Biology to Drug Delivery
This reference book discusses the role of synbiotics in a wide range of disease states, including cardiovascular, reproductive, metabolic, neurodegenerative, gastrointestinal, thrombotic, skin, and inflammatory disorders. It reviews the functions of probiotics in the diagnosis, prevention, or treatment of various disease states. The book further covers improving the targeting efficiency of synbiotics through advanced drug delivery systems such as nanoparticles, microparticles, liposomes, microemulsion, solid lipid nanoparticles, and nano lipid carriers. The chapter addresses the implications of oral and topical delivery of synbiotics in different diseases and presents the safety assessment o...
Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective
Nanotechnology has revolutionized cancer diagnosis and therapy through targeted drug delivery. Advances in protein engineering and materials science have led to the development of nanocarriers (NCs), which have helped overcome the challenges faced during conventional cancer treatment. These nanocarriers serve as an efficient transport module for drugs. Nano-drug delivery has emerged as a promising technology that results in early detection and better treatment of various cancers. The approved nanoparticles currently used in cancer treatment strategies include liposomes, dendrimers, polyplexes, solid lipid nano-carriers, etc. These nanocarriers can potentially provide a quick, safe, and cost-...
Nanomanufacturing Techniques in Sustainable Healthcare Applications
The text begins by discussing the processing and characterization of nano-manufactured resorbable bionanocomposites and presents the latest advances in carbon-based polymer nanocomposite materials for sensing applications. It further presents different characterization techniques such as scanning electron, transmission electron, atomic force microscopy, and powder X-ray diffraction for the identification of bionanocomposites. This book: • Introduces nano-manufactured processed composites for biomedical application, processing, and characterization of bionanocomposites. • Presents biobased nano-manufactured processed composites for imaging, tissue repairing, and drug-delivery applications...
Sustainable Green Nanotechnology
The book places a strong emphasis on the significance of synthesizing nanomaterials and explores various methods of achieving this, with particular attention given to the production of environmentally friendly or "green" nanomaterials. This book illustrates the current gaps in the agriculture and food industry, and explores the potential applications of nanomaterials within this field. The integration of nanotechnology into the fields of biology and biochemistry holds the potential to exert a significant impact on the food industry in the future. This book comprehensively explores the various facets of design, utilization, and implementation of green nanomaterials within the agriculture and ...
Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases
Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases delves into the intricate mechanisms underlying neurodegenerative disorders and highlights cutting-edge diagnostic methods and innovative immunotherapeutic strategies. This comprehensive book addresses several key themes crucial to understanding and combating these debilitating conditions with an updated understanding of neurodegenerative disorders and a review of the latest advancements in diagnostic and treatment strategies. Key Themes Neuroinflammation: examines the complex molecular pathways involved in neuroinflammatory responses and their impact on disease dynamics. Gut-Brain Axis: A thorough discussion on th...
Emerging Paradigms in Delivery Systems for Antitubercular Therapy
Emerging Paradigms in Delivery Systems for Antitubercular Therapy provides an up-to-date and thorough overview of the state-of-the-art of concepts, design, and recent advances in nanomedicines and nanobiotechnology-based strategies for the treatment of tuberculosis. The book enables researchers to prepare a variety of nanotechnology-based strategies, investigate their properties, and discover their uses and applications in antitubercular therapy, focusing on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, and tuberculosis vaccination.This book covers all major topics that have shaped the development of nanomedicine and propelled it to its current place ...
Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications
This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
Role of Gut Microbiota and Postbiotics for Colorectal Cancer
The emerging role of gut microbiota and postbiotics has implications for the management of not only human health and diseases, but also colorectal cancer in particular, as these elements influence colorectal cancer pathogenesis, treatment, and prevention. This book bridges the gap between cutting-edge research and practical clinical applications in the management of colorectal cancer by offering a fresh perspective on potential therapeutic strategies and exploring the significance of microbiota in the oncology landscape. Chapters delve into the specific impacts of postbiotics, linking them to immune response modulation, inflammation reduction, and direct anticancer effects. Chapters also exp...
Signaling Pathways in Breast Cancer
Signaling Pathways in Breast Cancer: Molecular Mechanisms, Therapeutic Strategies, and Multidrug Resistance provides an in-depth exploration of the complex molecular mechanisms that drive breast cancer progression. The book focuses on critical signaling pathways, including PI3K/Akt/mTOR, MAPK/ERK, JAK/STAT, Wnt/?-catenin, and Notch, elucidating their roles in tumor development, survival, and therapeutic resistance. The content offers a comprehensive overview of these pathways, detailing their dysregulation in breast cancer and the implications for targeted therapeutic strategies. It discusses FDA-approved treatments, emerging therapies, and the mechanisms behind drug resistance, integrating recent research findings to highlight novel molecular targets and biomarker discovery. This book serves as a valuable resource for researchers, clinicians, and students, bridging the gap between basic molecular biology and clinical applications. By providing structured insights into complex signaling networks and therapeutic interventions, it equips the audience with essential knowledge for developing innovative approaches to breast cancer management and improving patient outcomes.
