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Good Research Practice in Non-Clinical Pharmacology and Biomedicine
This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine
Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop.
Immunological Mechanisms and Therapies in Brain Injuries and Stroke
Recent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes.
Virus Mania
"The book 'Virus Mania' has been written with the care of a master-craftsman, courageously evaluating the medical establishment, the corporate elites and the powerful government funding institutions." Wolfgang Weuffen, MD, Professor of Microbiology and Infectious Epidemiology "The book 'Virus-Wahn' can be called the first work in which the errors, frauds and general misinformations being spread by official bodies about doubtful or non-virus infections are completely exposed." Gordon T. Stewart, MD, professor of public health and former WHO advisor - - - The population is terrified by reports of so-called COVID-19, measles, swine flu, SARS, BSE, AIDS or polio. However, the authors of "Virus M...
Primer on Cerebrovascular Diseases
A handy reference source for scientists, students and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The books consists of short, specific chapters written by international experts on cerebral vasculature, and presents the information in a comprehensive and easily accessible manner.
Handbook of Organic Compounds: Methods and interpretations
For students and vibrational spectroscopists working in molecular spectroscopy labs and dealing daily with spectral interpretation and data processing of organic spectra, polymers, and surfactants. This three-volume compendium contains detailed descriptions and reviews of ultraviolet, visible, near-infrared, Raman, and dielectric measurement techniques, as well as interpretive techniques, and information on all spectra, which are presented in terms of wavenumber and transmittance. Ultraviolet, visible, 4th-overtone NIR, 3rd-overtone NIR, and NIR spectra are also presented in terms of nanometers and absorbance space; and horizontal ATR spectra are presented in terms of wavenumber and absorbance space. The spectra found here are useful for identification purposes as well as for instruction in the various interpretive and data-processing techniques discussed. Editor Workman is employed at Kimberly-Clark Corporation. c. Book News Inc.
Neuroprotection
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
Cerebrovascular Diseases
The Nineteenth Princeton Conference on Cerebrovascular Disease provided a unique forum for national and international experts to present and discuss state-of-the-art research in the field of stroke. The Conference was hosted by the Massachusetts General Hospital and held in Boston in 1994.
