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The Long Haul
How survivors of the Covid-19 pandemic battling long-term disabling conditions are fighting for recognition and research—and helping to transform healthcare for many overlooked diseases. To the world’s public health authorities, Covid-19 would be either a deadly disease for some or a simple respiratory illness for most, its symptoms clearing up in just a matter of weeks. But then tens of millions around the world got sick and stayed sick. With scientists and doctors caught off guard, these Long Covid patients often found solace only with one another, organizing support groups across oceans and continents while ill in bed. In The Long Haul, CNN journalist Ryan Prior weaves his own life, t...
The Long Covid Handbook
Understand, manage, and treat Long Covid. Reports suggest that over 100m people around the world are living with Long Covid (more than 1.5m in the UK) yet reliable, clear information and guidance remains scarce. This book is the definitive guide to understanding, managing and treating the condition. Written by the world's leading immunologist Professor Danny Altmann and expert patient Gez Medinger, The Long Covid Handbook translates cutting-edge science, patient-led research and practical guidance with clarity. This book will equip you with expert information and advice on: - Long Covid's 200 symptoms, which include fatigue, brain fog, breathlessness and more - Tips for recovery - Which treatments are most effective and why - Who is most susceptible to the condition and why - What we can learn about Long Covid from other chronic illnesses - The impact on mental health This is the essential guide for anyone living with the condition, as well as clinicians seeking to better understand this little-understood illness.
Changes in T Cell Populations and Cytokine Production in SARS-CoV-2 Infected Individuals; Their Role in Prognosis
At the time of writing this call for papers for the special issue: “Changes in T cell populations and cytokine production in SARS-CoV-2 infected individuals; their role in prognosis” (June 10, 2022), over 534 million people have been infected with SARS-CoV-2 virus, of whom over 6.3 million have died. Early studies of COVID-19 reported that infection with SARS‐CoV‐2 results in dysregulation of the immune and hematopoietic systems, manifested by lymphopenia, increased numbers of hyperactivated neutrophils and NK cells, and the development of tolerogenic APCs that suppress T-cell-mediated immunity. In patients with COVID-19, lymphopenia, mainly due to depletion of effector T cells, with...
Systems Medicine
Why do we get certain diseases, whereas other diseases do not exist? In this book, Alon, one of the founders of systems biology, builds a foundation for systems medicine. Starting from basic laws, the book derives why physiological circuits are built the way they are. The circuits have fragilities that explain specific diseases and offer new strategies to treat them. By the end, the reader will be able to use simple and powerful mathematical models to describe physiological circuits. The book explores, in three parts, hormone circuits, immune circuits, and aging and age-related disease. It culminates in a periodic table of diseases. Alon writes in a style accessible to a broad range of readers - undergraduates, graduates, or researchers from computational or biological backgrounds. The level of math is friendly and the math can even be bypassed altogether. For instructors and readers who want to go deeper, the book includes dozens of exercises that have been rigorously tested in the classroom
AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
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