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Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure. It accounts for approximately 1.8% of all hematologic and solid cancers and slightly > 15% of hematologic malignancies in the United States. MM is typically sensitive to different classes of cytotoxic drugs, both as frontline treatment and as treatment for relapsed disease. Unfortunately, even if responses are typically durable, nowadays MM is not considered curable with current approaches. However, MM survival rates have been brilliantly improved thanks to the introduction of novel agents: patients diagnosed after 2010 have had higher rates of novel therapy use and better survival outcomes compared with those of earlier years. Most relevant therapeutic advances over the past decades has been the introduction of novel therapies, such as immune-modifying agents (thalidomide and lenalidomide) and proteasome inhibitors (bortezomib), adopted with or without stem cell transplantation.
Transformative Learning Theory and Praxis examines the multi-faceted nature of transformative learning and transformation theory including its merits, restrictions, and possibilities, and presents carefully chosen international case studies and theoretical approaches that enrich the application of the theory within a wide variety of educational settings. By including new approaches to transformative learning theory, this book provides examples and teaching approaches coming from a variety of disciplines, including higher education, arts, classics, new technologies, and academic development. It bridges the gap between theory and practice to help teachers and adult educators embed potentially ...
The book is the final report of the researches, discussions, conversations around and about the Project PRIN Employability & Competences which took place on March 9th-‐11th, 2017 within an International Conference at the University of Florence. It was the final event of the project PRIN2012LATR9N which aims were: «to design innovative programs for higher education, to promote personalized and learner-centered teaching and learning, to build on job competencies, to value talents to create new work opportunities, to support young adults during their employment emergency, as a response to socio economic crisis and as a citizenship action». The research activities concerned the main phases of the students’ academic life: career guidance upon entry, personalized teaching, career calling, professional vocation, profession building activities such as internships and work related experiences, and lastly job placement.
Earning a doctorate can be a daunting, yet rewarding, venture; the doctoral journey can include immeasurable sacrifice (e.g., health, family, finances). This edited volume—a collective narrative—comprises diverse educationalist perspectives from scholars who have successfully navigated the doctoral journey. Clearly articulated throughout this collective narrative, there are innumerable ways to complete the doctoral journey; the laborious journey is not a linear process but rather a lattice of ever-evolving professional and personal relationships, experiences, perspectives, and insights. Personal accounts of resilience and growth serve as sources of inspiration while offering sage advice, genuine insights, and significant analyses—all seamlessly connected. Contributors are: Laurie Hill, Makie Kortjass, Michael Paul Lukie, Ntokozo Mkhize-Mthembu, David G. Ngatia, Heather Raymond, Alessandra Romano, Pearl Subban, Kathy Toogood and Barbara van Ingen.
This book provides qualitative analyses of intercultural sense making in a variety of institutional contexts. It relies on the assumption that in an increasingly culturally diverse world, individuals often enter contexts that have communal, historically determined and stable sets of values, norms and expected identities, with little cultural compass to find their bearings in them. The book goes beyond interpreting differences in people’s ethnic or linguistic roots and discusses instead people’s interpretive efforts to navigate different sociocultural situations. The contributors examine such situations in educational, organizational, medical and community settings and look at how participants with different levels of sociocultural competences (such as, migrant patients, migrant adult learners, children) try to cope with institutional constraints and expectations, how they understand symbols, practices and identities in institutional contexts, and how their creative adjustments come to light. This book provides insights from the fields of psychology, education, anthropology and linguistics, and is for a wide readership interested in cultural meaning-making.
The main objective of FEEMCE 2013 is to provide a platform for researchers, engineers, academicians as well as industrial professionals from all over the world to present their research results and development activities in Energy, Environmental Materials and Civil Engineering. This conference provides opportunities for the delegates to exchange new ideas and experiences face to face, to establish business or research relations and to find global partners for future collaboration.
Offering insights into the adaptational strategies that were employed by higher education institutions worldwide during the Covid-19 pandemic, this volume considers the lasting effects of adaptation and change, as well as the perception of universities’ role in society and desired ways of operating. Nearly overnight, the pandemic forced university leaders and faculty across the world to switch to remote models, not only of teaching and learning but also of managing an entire institution. This book recognizes how the scale of challenges as well as the range of measures specific universities had to undertake was uneven, with some being better equipped than the others. Using a selection of in...
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Vols. 1-4 include material to June 1, 1929.