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Innovative Bioceramics in Translational Medicine I
This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume covers the basic principles and techniques used in the manufacture of bioceramics and biocomposites for various biomedical applications including drug delivery, implantable bionics and the development of the cardiac pacemaker, and bone tissue engineering. Furthermore, self-healing materials have been attracting increasing interest in both engineering and medical applications during the past two decades. Self-healing hydrogels are particularly interesting because of their ability to repair structural damages and recover their original functions, specifically in tissue engineering.
Biomimetic biomaterials
Scientific research on tissue regeneration is increasingly becoming the most promising response to a number of disabling pathologies with huge impact on the progressively growing and ageing world population. The biomimicry of scaffolds with the target tissue is now universally considered to be a key requirement to properly instruct cells towards the restoration of physiological functioning. In this respect, the present chapter presents an overview of recent findings on biomimetic materials and devices addressed to bone and osteochondral tissues as well as soft organ regeneration. Particular focus is given to new apatite phases, including the newly discovered superparamagnetic apatite and processes to develop ceramic, polymeric and hybrid regenerative scaffolds.
Biomimetic biomaterials
Recent advances in stem cell biology and tissue engineering have paved the way for new therapies for incurable diseases and replacement of tissues and/or organs. These therapies rely on biomaterial mimicking involving niches to control the fate of stem cells and produce stem cell-based tissues. The niches or biomimetic scaffolds can be used for long-term maintenance and lineage-specific differentiation of stem cells. This chapter introduces a method for creation of biomimetic scaffolds. Acellular scaffolds were obtained by removing the cellular components of natural tissues. Then, human stem cells were isolated and cultured on these scaffolds.
Biomimetic biomaterials
This chapter investigates the concept of hierarchy widely found in biological materials. First, natural hierarchical materials are explored in terms of their high order structures formed from universal building blocks. Hierarchical arrangement is claimed to give rise to remarkable mechanical properties of biological structures. Therefore at the next step, the significance of hierarchical structuring on mechanical properties is investigated through available analytical models. Finally, fabrication methods which could potentially lead to artificial hierarchical structures are briefly reviewed in the domain of biomimetics.
Metal-Reinforced Ceramics
Metal-Reinforced Ceramics covers the principle of metal-fiber-reinforced ceramics, a well-known topic in the field of reinforced concrete. Much of the work that has been done has remained unpublished, hidden in industrial company archives due to the commercial sensitivity associated with the respective technologies that prevailed at the time, which no longer applies today. This book will discuss advanced technologies that have largely been undocumented before in a broad range of industrial application areas, with updates on alumina, silicon carbide, boron carbide, tungsten carbide, fused silica, and carbon-based ceramics which are hard, heat resistant, wear resistant, and chemically durable. - Provides detailed information on fundamental principles, advanced processing technologies and industrial applications - Features comprehensive industrial knowledge not usually in the public domain from the author's experience spanning more than three decades - Features armor ceramics, bioceramics, aerospace, mining and architectural ceramic applications
Alumina Ceramics
Alumina Ceramics: Biomedical and Clinical Applications examines the extraordinary material, Alumina, and its use in biomedicine and industry. Sections discuss the fundamentals of Alumina Ceramics, look at the various industrial applications, and examine a variety of medical applications. Readers will find this to be an invaluable and unique resource for researchers, clinical professionals, engineers, and advanced level students. Alumina ceramics are a leading biomaterial used for specialist medical applications, such as bionic implants and tissue engineering, and the only biomaterial commercially viable for use as bearings for orthopedic hip replacements. As such, this book is a timely resource on the topics discussed. - Provides a unique and thorough review of Alumina ceramics - Written by one of the world's leading experts in bioceramics and advanced industrial ceramics, especially alumina - Targeted to researchers in the materials, clinical and dental fields - Enables the non-expert with an overview of the underlying alumina technology, major challenges, major successes and future directions
Advanced Ceramic Coatings and Interfaces, Volume 27, Issue 3
Recent advances in coating development, processing, microstructure and property characterization, and life prediction are included in this book, which came from the proceedings of the 30th International Conference on Advanced Ceramics and Composites, January 22-27, 2006, Cocoa Beach, Florida. Organized and sponsored by The American Ceramic Society and The American Ceramic Society's Engineering Ceramics Division in conjunction with the Nuclear and Environmental Technology Division.. Integrated structural, environmental properties and functionality through advanced coating processing and structural design are emphasized in this book.
