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Monocytes and Macrophages in Development, Regeneration, and Disease
The study and therapeutic application of macrophages is a rapidly developing field. Tremendous progress has been made in understanding the phenotypes and functions of macrophages in healthy and diseased tissues and organs. Following the great success of Volume 62: "Macrophages - Origin, Functions and Biointervention" published in this series, this new book now focuses on the role of monocytes and macrophages in development, regeneration and disease. This new volume offers an overview of the latest developments in monocyte and macrophage subtypes and functions across various tissues including adipose tissue, bones, liver, lungs, testes, and the nervous system. The book also reviews existing a...
Cancer
Cancer: Oxidative Stress and Dietary Antioxidants, Second Edition, covers the science of oxidative stress in cancer and the potentially therapeutic usage of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor-mediated responses. This approach recognizes that diseases are often multifactorial and that oxidative stress is a single component. Other sections cover new organ site tumors—skin and liver cancer, the role of polymorphisms, cytochrome p450s, COX gene, fatty acids, apoptosis, T cells and mitochondria, prevention/protection with anthocyanins,...
Cellular and Molecular Mechanisms of Chronic Rejection in Organ Transplantation
Despite improvements in antirejection therapies, solid organ transplantation is hampered by chronic rejection, with around 70% of transplants being rejected within 10 years post-transplantation. Given the growing number of transplant candidates and the shortage of organ donors, finding a cure for chronic rejection is a priority in transplantation. Although chronic rejection studies have increased our knowledge of the subject over the years, the cellular and molecular processes involved in chronic rejection are still not fully understood. This volume covers the molecular and cellular aspects of the chronic rejection of both solid and composite allografts. It is divided into three parts: Part ...
Histone and Non-Histone Reversible Acetylation in Development, Aging and Disease
This volume explores various aspects of reversible acetylation of histone and non-histone proteins, focusing on their roles in development, ageing and disease progression. It examines the biological consequences of modulating acetylation levels by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Covered are manipulations at multiple levels, from in vitro and in vivo studies to clinical trials and FDA-approved therapies. The book is divided in four parts: !--[endif]--Part I provides an overview of post-translational modifications in the context of development, ageing, neurodegenerative and cancer-related diseases. It highlights the role of histone acetylation in higher geno...
Women in the Ukrainian Underground
The inclusion of eastern Poland into the Soviet Union by the 1939 Molotov–Ribbentrop Pact initiated a long and bloody resistance of local Ukrainian population to Soviet rule. Even after the end of the Second World War, the Organization of Ukrainian Nationalists (OUN) and the Ukrainian Insurgent Army (UPA) persisted in their fight for an independent Ukrainian state. The continued confrontations between the Ukrainian underground and Soviet security service lasted until the late 1950s. While existing scholarship has focussed mainly on the political aspects of this conflict, women’s participation in opposing Sovietization remained largely ignored. Women in the Ukrainian Underground foregroun...
Ornamentalism
Original essays by leading scholars on the significance of accessories in the cultural, social, and political lives of men and women in the Renaissance
