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Meeting abstracts of the 3° EVIta symposium
The 3rd Symposium of the Italian Society of Extracellular Vesicles (The 3° EVIta Symposium), September 13-15, 2023 [Table 1].
Cytokines as Players of Neuronal Plasticity and Sensitivity to Environment in Healthy and Pathological Brain
It is now accepted that immune molecules are not only present within the brain during pathology but they exert physiological functions in the “healthy” brain as well. Increasing evidence points to a neuro-modulatory role of cytokines and chemokines (CHEMOtactic cytoKINES) in basal transmission and plasticity processes where signaling between peri-synaptic astrocytes, microglia and neurons plays an important role. Nevertheless, the exact mechanisms as to how cytokines, and in particular chemokines, participate in the molecular and cellular processes thought to subserve memory formation, plasticity processes and responsiveness to environmental stimuli remain to be clarified. Interestingly,...
Glioma Signaling
Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumor, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. This book is a reference on cellular signaling processes regulating gliomas physiology and invasiveness. The work is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides and formation of complex signaling cascades induced by growth factors, cytokines and cannabinoids. The second edition of the book enriched in new chapters provides a framework explaining how signal transduction elements may modulate numerous genetic and epigenetic alterations, describes the role of local microenvironment in cellular growth, progression and invasion and, in the light of extensive new results, presents perspectives concerning potential targets for gliomas therapy.
Chemokines and Chemokine Receptors in Brain Homeostasis
Virtually involved in all pathologies that present an inflammatory component, it is now evident that, in the central nervous system, chemokines and chemokine receptors possess pleiotropic properties beyond chemotaxis: costitutive brain expression of chemokines and their receptors on endothelial cells, but also on neurons and glia, suggests a role for such molecules in mediating homeostatic cross-talk between cells of the brain perenchyma. Cross-talk between neurons and glia is determinant to the establishment and maintenance of a brain enviroment that ensure normal function, and in particular glial cells are active players that respond to enviromental changes and act for the survival, growth...
Dual Role of Microglia in Health and Disease: Pushing the Balance Towards Repair
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
The First Outstanding 50 Years of “Università Politecnica delle Marche”
The book describes the significant multidisciplinary research findings at the Università Politecnica delle Marche and the expected future advances. It addresses some of the most dramatic challenges posed by today’s fast-growing, global society and the changes it has caused. It also discusses solutions to improve the wellbeing of human beings. The book covers the main research achievements in the various disciplines of the life sciences, and includes chapters that highlight mechanisms relevant to all aspects of human diseases, the molecular, cellular, and functional basis of therapy, and its translation into the management of people’s health needs. It also describes research on tradition...
74th Annual Meeting of the Italian Society of Physiology: Breakthroughs and Key Discoveries
The 74th Congress of the Italian Society of Physiology (SIF) featured a rich scientific program, with plenary lectures, symposia, and oral communications presented by esteemed experts and promising young scientists. The SIF Congress then provides a valuable opportunity for discussing the latest developments in research areas dealing with basic and translational physiology. This Frontiers Research Topic aims to highlight a selection of high-quality contributions, ranging from original research articles to comprehensive reviews, submitted by researchers attending the SIF conference. We also encourage contributions from those in the field of Physiology who were unable to attend the congress.
From Latin to Romance
This book examines grammatical changes during the transition from Latin to the Romance languages and the factors proposed to explain them. It challenges orthodoxy, presents new perspectives on language change, structure, and variation, and will appeal equally to Romance linguists, Latinists, philologists, and historical linguists of all persuasions.
