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Read, laugh and learn a little French. Go with puppy Amberella from the farm to the city. Two funny, spoiled poodle sisters, Zozue and Tutsu, live there with a grandmother who has a secret. Amberella must make friends with the poodles. Can little Amberella do this and will the grandmother's secret help her? Follow Amberella's adventures during her first year. See if she will live happily ever after when she meets a prince. Readers will love the dogs in this book and never forget them.
Even though these poems were written when Ms. Macklin was fift years old, they express the little girl in her, the child who suffered the pain and despair of growing up with alcoholic parents. She accompanies her poetry with her thoughts on addiction and with a brief but inspiring account of her recovery. Complementing and reinforcing the poems is a section displaying the handiwork of sixth-graders who responded to Ms. Macklin's poems wit crayon drawings and short essays describing the effects of alcohol and drugs in their own families.
The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including cancer, neurodegenerative, age-related, mtDNA depletion, deletion, and point m...
After her mother's untimely death, seven-year-old Abigail must endure an alcoholic stepfather, a well-meaning but unsavory orphanage, and a grandfather ruled by a designing woman. The traumatic seeds of Abigail's unstable childhood grow, flourish and pervade her adolescence and marriage.
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