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Glycans play essential roles in diverse biological and etiological processes and their structural complexity endow various functions. The glycome is the entire set of glycans produced by an individual organism. As the glycan microarray emerged, a good amount of knowledge has been obtained in understanding the functions of glycans. However, limited accessibility of glycans is a major obstacle to the functional glycomics study. Although isolation from biology samples provided some structures, the low abundance of glycans obtained and the difficulty in complete structural assignment restricted the subsequent assay. To circumvent this limitation, many synthetic strategies, including chemical, en...
Glycans play essential roles in diverse biological and etiological processes and their structural complexity endow various functions. The glycome is the entire set of glycans produced by an individual organism. As the glycan microarray emerged, a good amount of knowledge has been obtained in understanding the functions of glycans. However, limited accessibility of glycans is a major obstacle to the functional glycomics study. Although isolation from biology samples provided some structures, the low abundance of glycans obtained and the difficulty in complete structural assignment restricted the subsequent assay. To circumvent this limitation, many synthetic strategies, including chemical, en...
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
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Luo Ping (1733-1799), known as the youngest of the Eight Eccentrics of Yangzhou and a follower of Jin Nong (1687-1763), was one of the most versatile and compelling artists of his time. While his work covers all major painting subjects and exhibits great stylistic and conceptual variety, his personality appears equally multifaceted. Contemporaries and later critics characterized him variously as a cultural arriviste, a Confucian scholar of great moral dignity, a Buddhist monk, a loving and devout husband, an - eccentric with strong leanings toward the supernatural, and even an anti-Manchu dissident. Structured as a comprehensive and largely chronological account of the artist's life and his interactions with patrons of different geo-cultural environs, namely Yangzhou and Beijing, this study attempts to identify the factors that contributed to the unfolding of the master's artistic voice. It includes an extensive examination of Luo's personal, literary, and artistic engagement with Buddhism, which constituted a significant but hitherto obscure facet of his life and work."
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